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Preclinical Pharmacology and Pharmacokinetics of Inhaled Hexadecyl-Treprostinil (C16TR), a Pulmonary Vasodilator Prodrug.
Corboz MR, Li Z, Malinin V, Plaunt AJ, Konicek DM, Leifer FG, Chen KJ, Laurent CE, Yin H, Biernat MC, Salvail D, Zhuang J, Xu F, Curran A, Perkins WR, Chapman RW. Corboz MR, et al. Among authors: curran a. J Pharmacol Exp Ther. 2017 Dec;363(3):348-357. doi: 10.1124/jpet.117.242099. Epub 2017 Sep 13. J Pharmacol Exp Ther. 2017. PMID: 28904003
CXCR2 antagonists for the treatment of pulmonary disease.
Chapman RW, Phillips JE, Hipkin RW, Curran AK, Lundell D, Fine JS. Chapman RW, et al. Among authors: curran ak. Pharmacol Ther. 2009 Jan;121(1):55-68. doi: 10.1016/j.pharmthera.2008.10.005. Epub 2008 Oct 31. Pharmacol Ther. 2009. PMID: 19026683 Review.
A phase 1/1b study of PUR1900, an inhaled formulation of itraconazole, in healthy volunteers and asthmatics to study safety, tolerability and pharmacokinetics.
Hava DL, Tan L, Johnson P, Curran AK, Perry J, Kramer S, Kane K, Bedwell P, Layton G, Swann C, Henderson D, Khan N, Connor L, McKenzie L, Singh D, Roach J. Hava DL, et al. Br J Clin Pharmacol. 2020 Apr;86(4):723-733. doi: 10.1111/bcp.14166. Epub 2020 Jan 16. Br J Clin Pharmacol. 2020. PMID: 31696544 Free PMC article. Clinical Trial.
A New Natural Defense Against Airborne Pathogens.
Edwards D, Hickey A, Batycky R, Griel L, Lipp M, Dehaan W, Clarke R, Hava D, Perry J, Laurenzi B, Curran AK, Beddingfield BJ, Roy CJ, Devlin T, Langer R. Edwards D, et al. Among authors: curran ak. QRB Discov. 2020 Jul 7;1:e5. doi: 10.1017/qrd.2020.9. eCollection 2020. QRB Discov. 2020. PMID: 34192261 Free PMC article.
The monocyte cell surface is a unique site of autoantigen generation in rheumatoid arthritis.
Thomas MA, Naik P, Wang H, Giles JT, Girgis AA, Kim SY, Johnson TP, Curran AM, Crawford JD, Jahanbani S, Bingham CO, Robinson WH, Na CH, Darrah E. Thomas MA, et al. Among authors: curran am. Proc Natl Acad Sci U S A. 2024 Apr 23;121(17):e2304199121. doi: 10.1073/pnas.2304199121. Epub 2024 Apr 17. Proc Natl Acad Sci U S A. 2024. PMID: 38630712
Switching to dolutegravir plus rilpivirine versus maintaining current antiretroviral therapy regimen in virologically suppressed people with HIV-1 and the Lys103Asn (K103N) mutation: 48-week results from a randomised, open-label pilot clinical trial.
Moyle G, Assoumou L, de Castro N, Post FA, Curran A, Rusconi S, De Wit S, Stephan C, Raffi F, Johnson M, Masia M, Vera J, Jones B, Grove R, Fletcher C, Duffy A, Morris K, Pozniak A; NEAT ID Foundation and the WISARD study group. Moyle G, et al. Among authors: curran a. Lancet HIV. 2024 Mar;11(3):e156-e166. doi: 10.1016/S2352-3018(23)00292-8. Lancet HIV. 2024. PMID: 38417976 Clinical Trial.
Outcomes of Drug Interactions Between Antiretrovirals and Co-Medications, Including Over-the-Counter Drugs: A Real-World Study.
Ambrosioni J, Díaz NA, Marzolini C, Dragovic G, Imaz A, Calcagno A, Luque S, Curran A, Troya J, Tuset M, Khoo S, Burger D, Cortés CP, Naous N, Molto J. Ambrosioni J, et al. Among authors: curran a. Infect Dis Ther. 2024 Mar;13(3):609-617. doi: 10.1007/s40121-024-00935-0. Epub 2024 Feb 19. Infect Dis Ther. 2024. PMID: 38372897 Free PMC article.
496 results