D'Agostino VG - Search Results

1

Transcriptional induction of the heat shock protein B8 mediates the clearance of misfolded proteins responsible for motor neuron diseases.

Crippa V, D'Agostino VG, Cristofani R, Rusmini P, Cicardi ME, Messi E, Loffredo R, Pancher M, Piccolella M, Galbiati M, Meroni M, Cereda C, Carra S, Provenzani A, Poletti A. Crippa V, et al. Sci Rep. 2016 Mar 10;6:22827. doi: 10.1038/srep22827. Sci Rep. 2016. PMID: 26961006 Free PMC article.

2

A novel high throughput biochemical assay to evaluate the HuR protein-RNA complex formation.

D'Agostino VG, Adami V, Provenzani A. D'Agostino VG, et al. PLoS One. 2013 Aug 12;8(8):e72426. doi: 10.1371/journal.pone.0072426. eCollection 2013. PLoS One. 2013. PMID: 23951323 Free PMC article.

3

Targeting the multifaceted HuR protein, benefits and caveats.

Zucal C, D'Agostino V, Loffredo R, Mantelli B, NatthakanThongon, Lal P, Latorre E, Provenzani A. Zucal C, et al. Curr Drug Targets. 2015;16(5):499-515. doi: 10.2174/1389450116666150223163632. Curr Drug Targets. 2015. PMID: 25706256 Review.

4

Dihydrotanshinone-I interferes with the RNA-binding activity of HuR affecting its post-transcriptional function.

D'Agostino VG, Lal P, Mantelli B, Tiedje C, Zucal C, Thongon N, Gaestel M, Latorre E, Marinelli L, Seneci P, Amadio M, Provenzani A. D'Agostino VG, et al. Sci Rep. 2015 Nov 10;5:16478. doi: 10.1038/srep16478. Sci Rep. 2015. PMID: 26553968 Free PMC article.

5

The GSK3β inhibitor BIS I reverts YAP-dependent EMT signature in PDAC cell lines by decreasing SMADs expression level.

Thongon N, Castiglioni I, Zucal C, Latorre E, D'Agostino V, Bauer I, Pancher M, Ballestrero A, Feldmann G, Nencioni A, Provenzani A. Thongon N, et al. Oncotarget. 2016 May 3;7(18):26551-66. doi: 10.18632/oncotarget.8437. Oncotarget. 2016. PMID: 27034169 Free PMC article.

6

JNK1 ablation in mice confers long-term metabolic protection from diet-induced obesity at the cost of moderate skin oxidative damage.

Becattini B, Zani F, Breasson L, Sardi C, D'Agostino VG, Choo MK, Provenzani A, Park JM, Solinas G. Becattini B, et al. FASEB J. 2016 Sep;30(9):3124-32. doi: 10.1096/fj.201600393R. Epub 2016 May 26. FASEB J. 2016. PMID: 27230858 Free PMC article.

7

Different BCR/Abl protein suppression patterns as a converging trait of chronic myeloid leukemia cell adaptation to energy restriction.

Bono S, Lulli M, D'Agostino VG, Di Gesualdo F, Loffredo R, Cipolleschi MG, Provenzani A, Rovida E, Dello Sbarba P. Bono S, et al. Oncotarget. 2016 Dec 20;7(51):84810-84825. doi: 10.18632/oncotarget.13319. Oncotarget. 2016. PMID: 27852045 Free PMC article.

8

Interfering with HuR-RNA Interaction: Design, Synthesis and Biological Characterization of Tanshinone Mimics as Novel, Effective HuR Inhibitors.

Manzoni L, Zucal C, Maio DD, D'Agostino VG, Thongon N, Bonomo I, Lal P, Miceli M, Baj V, Brambilla M, Cerofolini L, Elezgarai S, Biasini E, Luchinat C, Novellino E, Fragai M, Marinelli L, Provenzani A, Seneci P. Manzoni L, et al. J Med Chem. 2018 Feb 22;61(4):1483-1498. doi: 10.1021/acs.jmedchem.7b01176. Epub 2018 Jan 31. J Med Chem. 2018. PMID: 29313684

9

Screening Approaches for Targeting Ribonucleoprotein Complexes: A New Dimension for Drug Discovery.

D'Agostino VG, Sighel D, Zucal C, Bonomo I, Micaelli M, Lolli G, Provenzani A, Quattrone A, Adami V. D'Agostino VG, et al. SLAS Discov. 2019 Mar;24(3):314-331. doi: 10.1177/2472555218818065. Epub 2019 Jan 7. SLAS Discov. 2019. PMID: 30616427 Free article. Review.

10

Proteostasis and ALS: protocol for a phase II, randomised, double-blind, placebo-controlled, multicentre clinical trial for colchicine in ALS (Co-ALS).

Mandrioli J, Crippa V, Cereda C, Bonetto V, Zucchi E, Gessani A, Ceroni M, Chio A, D'Amico R, Monsurrò MR, Riva N, Sabatelli M, Silani V, Simone IL, Sorarù G, Provenzani A, D'Agostino VG, Carra S, Poletti A. Mandrioli J, et al. BMJ Open. 2019 May 30;9(5):e028486. doi: 10.1136/bmjopen-2018-028486. BMJ Open. 2019. PMID: 31152038 Free PMC article.

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