DeFrees S - Search Results

1

ST6GalNAc-I controls expression of sialyl-Tn antigen in gastrointestinal tissues.

Marcos NT, Bennett EP, Gomes J, Magalhaes A, Gomes C, David L, Dar I, Jeanneau C, DeFrees S, Krustrup D, Vogel LK, Kure EH, Burchell J, Taylor-Papadimitriou J, Clausen H, Mandel U, Reis CA. Marcos NT, et al. Among authors: defrees s. Front Biosci (Elite Ed). 2011 Jun 1;3(4):1443-55. doi: 10.2741/e345. Front Biosci (Elite Ed). 2011. PMID: 21622148 Free article.

2

GlycoPEGylation of recombinant therapeutic proteins produced in Escherichia coli.

DeFrees S, Wang ZG, Xing R, Scott AE, Wang J, Zopf D, Gouty DL, Sjoberg ER, Panneerselvam K, Brinkman-Van der Linden EC, Bayer RJ, Tarp MA, Clausen H. DeFrees S, et al. Glycobiology. 2006 Sep;16(9):833-43. doi: 10.1093/glycob/cwl004. Epub 2006 May 22. Glycobiology. 2006. PMID: 16717104

3

The synthesis of sialylated oligosaccharides using a CMP-Neu5Ac synthetase/sialyltransferase fusion.

Gilbert M, Bayer R, Cunningham AM, DeFrees S, Gao Y, Watson DC, Young NM, Wakarchuk WW. Gilbert M, et al. Among authors: defrees s. Nat Biotechnol. 1998 Aug;16(8):769-72. doi: 10.1038/nbt0898-769. Nat Biotechnol. 1998. PMID: 9702777

4

Variants of the beta 1,3-galactosyltransferase CgtB from the bacterium Campylobacter jejuni have distinct acceptor specificities.

Bernatchez S, Gilbert M, Blanchard MC, Karwaski MF, Li J, Defrees S, Wakarchuk WW. Bernatchez S, et al. Among authors: defrees s. Glycobiology. 2007 Dec;17(12):1333-43. doi: 10.1093/glycob/cwm090. Epub 2007 Aug 30. Glycobiology. 2007. PMID: 17766267

5

Expression of active human sialyltransferase ST6GalNAcI in Escherichia coli.

Skretas G, Carroll S, DeFrees S, Schwartz MF, Johnson KF, Georgiou G. Skretas G, et al. Among authors: defrees s. Microb Cell Fact. 2009 Sep 30;8:50. doi: 10.1186/1475-2859-8-50. Microb Cell Fact. 2009. PMID: 19788761 Free PMC article.

6

Structural insight into mammalian sialyltransferases.

Rao FV, Rich JR, Rakić B, Buddai S, Schwartz MF, Johnson K, Bowe C, Wakarchuk WW, Defrees S, Withers SG, Strynadka NC. Rao FV, et al. Among authors: defrees s. Nat Struct Mol Biol. 2009 Nov;16(11):1186-8. doi: 10.1038/nsmb.1685. Epub 2009 Oct 11. Nat Struct Mol Biol. 2009. PMID: 19820709

7

A Bacterial Expression Platform for Production of Therapeutic Proteins Containing Human-like O-Linked Glycans.

Du T, Buenbrazo N, Kell L, Rahmani S, Sim L, Withers SG, DeFrees S, Wakarchuk W. Du T, et al. Among authors: defrees s. Cell Chem Biol. 2019 Feb 21;26(2):203-212.e5. doi: 10.1016/j.chembiol.2018.10.017. Epub 2018 Nov 29. Cell Chem Biol. 2019. PMID: 30503285 Free article.

8

Glycosynthase-mediated synthesis of glycosphingolipids.

Vaughan MD, Johnson K, DeFrees S, Tang X, Warren RA, Withers SG. Vaughan MD, et al. Among authors: defrees s. J Am Chem Soc. 2006 May 17;128(19):6300-1. doi: 10.1021/ja058469n. J Am Chem Soc. 2006. PMID: 16683778

9

Synthetic GM1 improves motor and memory dysfunctions in mice with monoallelic or biallelic disruption of GM3 synthase.

Chowdhury S, Kumar R, Zepeda E, DeFrees S, Ledeen R. Chowdhury S, et al. Among authors: defrees s. FEBS Open Bio. 2023 Sep;13(9):1651-1657. doi: 10.1002/2211-5463.13669. Epub 2023 Jul 13. FEBS Open Bio. 2023. PMID: 37401916 Free PMC article.

10

Mice deficient in GM1 manifest both motor and non-motor symptoms of Parkinson's disease; successful treatment with synthetic GM1 ganglioside.

Wu G, Lu ZH, Seo JH, Alselehdar SK, DeFrees S, Ledeen RW. Wu G, et al. Among authors: defrees s. Exp Neurol. 2020 Jul;329:113284. doi: 10.1016/j.expneurol.2020.113284. Epub 2020 Mar 9. Exp Neurol. 2020. PMID: 32165255

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