DeMartino JA - Search Results

1

The amino terminus of the human C5a receptor is required for high affinity C5a binding and for receptor activation by C5a but not C5a analogs.

DeMartino JA, Van Riper G, Siciliano SJ, Molineaux CJ, Konteatis ZD, Rosen H, Springer MS. DeMartino JA, et al. J Biol Chem. 1994 May 20;269(20):14446-50. J Biol Chem. 1994. PMID: 8182049 Free article.

2

Two-site binding of C5a by its receptor: an alternative binding paradigm for G protein-coupled receptors.

Siciliano SJ, Rollins TE, DeMartino J, Konteatis Z, Malkowitz L, Van Riper G, Bondy S, Rosen H, Springer MS. Siciliano SJ, et al. Proc Natl Acad Sci U S A. 1994 Feb 15;91(4):1214-8. doi: 10.1073/pnas.91.4.1214. Proc Natl Acad Sci U S A. 1994. PMID: 8108389 Free PMC article.

3

Cloning, expression, and characterization of the human eosinophil eotaxin receptor.

Daugherty BL, Siciliano SJ, DeMartino JA, Malkowitz L, Sirotina A, Springer MS. Daugherty BL, et al. Among authors: demartino ja. J Exp Med. 1996 May 1;183(5):2349-54. doi: 10.1084/jem.183.5.2349. J Exp Med. 1996. PMID: 8642344 Free PMC article.

4

Binding and functional properties of recombinant and endogenous CXCR3 chemokine receptors.

Weng Y, Siciliano SJ, Waldburger KE, Sirotina-Meisher A, Staruch MJ, Daugherty BL, Gould SL, Springer MS, DeMartino JA. Weng Y, et al. Among authors: demartino ja. J Biol Chem. 1998 Jul 17;273(29):18288-91. doi: 10.1074/jbc.273.29.18288. J Biol Chem. 1998. PMID: 9660793 Free article.

5

A critical site in the core of the CCR5 chemokine receptor required for binding and infectivity of human immunodeficiency virus type 1.

Siciliano SJ, Kuhmann SE, Weng Y, Madani N, Springer MS, Lineberger JE, Danzeisen R, Miller MD, Kavanaugh MP, DeMartino JA, Kabat D. Siciliano SJ, et al. Among authors: demartino ja. J Biol Chem. 1999 Jan 22;274(4):1905-13. doi: 10.1074/jbc.274.4.1905. J Biol Chem. 1999. PMID: 9890944 Free article.

6

Arginine 206 of the C5a receptor is critical for ligand recognition and receptor activation by C-terminal hexapeptide analogs.

DeMartino JA, Konteatis ZD, Siciliano SJ, Van Riper G, Underwood DJ, Fischer PA, Springer MS. DeMartino JA, et al. J Biol Chem. 1995 Jul 7;270(27):15966-9. doi: 10.1074/jbc.270.27.15966. J Biol Chem. 1995. PMID: 7608153 Free article.

7

Antagonists of the human CCR5 receptor as anti-HIV-1 agents. part 1: discovery and initial structure-activity relationships for 1 -amino-2-phenyl-4-(piperidin-1-yl)butanes.

Dorn CP, Finke PE, Oates B, Budhu RJ, Mills SG, MacCoss M, Malkowitz L, Springer MS, Daugherty BL, Gould SL, DeMartino JA, Siciliano SJ, Carella A, Carver G, Holmes K, Danzeisen R, Hazuda D, Kessler J, Lineberger J, Miller M, Schleif WA, Emini EA. Dorn CP, et al. Among authors: demartino ja. Bioorg Med Chem Lett. 2001 Jan 22;11(2):259-64. doi: 10.1016/s0960-894x(00)00637-5. Bioorg Med Chem Lett. 2001. PMID: 11206473

8

Antagonists of the human CCR5 receptor as anti-HIV-1 agents. Part 2: structure-activity relationships for substituted 2-Aryl-1-[N-(methyl)-N-(phenylsulfonyl)amino]-4-(piperidin-1-yl)butanes.

Finke PE, Meurer LC, Oates B, Mills SG, MacCoss M, Malkowitz L, Springer MS, Daugherty BL, Gould SL, DeMartino JA, Siciliano SJ, Carella A, Carver G, Holmes K, Danzeisen R, Hazuda D, Kessler J, Lineberger J, Miller M, Schleif WA, Emini EA. Finke PE, et al. Among authors: demartino ja. Bioorg Med Chem Lett. 2001 Jan 22;11(2):265-70. doi: 10.1016/s0960-894x(00)00639-9. Bioorg Med Chem Lett. 2001. PMID: 11206474

9

1,3,4-Trisubstituted pyrrolidine CCR5 receptor antagonists. Part 1: discovery of the pyrrolidine scaffold and determination of its stereochemical requirements.

Hale JJ, Budhu RJ, Mills SG, MacCoss M, Malkowitz L, Siciliano S, Gould SL, DeMartino JA, Springer MS. Hale JJ, et al. Among authors: demartino ja. Bioorg Med Chem Lett. 2001 Jun 4;11(11):1437-40. doi: 10.1016/s0960-894x(01)00232-3. Bioorg Med Chem Lett. 2001. PMID: 11378372

10

1,3,4-Trisubstituted pyrrolidine CCR5 receptor antagonists. Part 3: polar functionality and its effect on anti-HIV-1 activity.

Hale JJ, Budhu RJ, Mills SG, MacCoss M, Gould SL, DeMartino JA, Springer MS, Siciliano SJ, Malkowitz L, Schleif WA, Hazuda D, Miller M, Kessler J, Danzeisen R, Holmes K, Lineberger J, Carella A, Carver G, Emini EA. Hale JJ, et al. Among authors: demartino ja. Bioorg Med Chem Lett. 2002 Oct 21;12(20):2997-3000. doi: 10.1016/s0960-894x(02)00605-4. Bioorg Med Chem Lett. 2002. PMID: 12270192

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