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Genome-wide meta-analysis of depression identifies 102 independent variants and highlights the importance of the prefrontal brain regions.
Howard DM, Adams MJ, Clarke TK, Hafferty JD, Gibson J, Shirali M, Coleman JRI, Hagenaars SP, Ward J, Wigmore EM, Alloza C, Shen X, Barbu MC, Xu EY, Whalley HC, Marioni RE, Porteous DJ, Davies G, Deary IJ, Hemani G, Berger K, Teismann H, Rawal R, Arolt V, Baune BT, Dannlowski U, Domschke K, Tian C, Hinds DA; 23andMe Research Team; Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium; Trzaskowski M, Byrne EM, Ripke S, Smith DJ, Sullivan PF, Wray NR, Breen G, Lewis CM, McIntosh AM. Howard DM, et al. Among authors: deary ij. Nat Neurosci. 2019 Mar;22(3):343-352. doi: 10.1038/s41593-018-0326-7. Epub 2019 Feb 4. Nat Neurosci. 2019. PMID: 30718901 Free PMC article.
Genome-wide association scan identifies a colorectal cancer susceptibility locus on 11q23 and replicates risk loci at 8q24 and 18q21.
Tenesa A, Farrington SM, Prendergast JG, Porteous ME, Walker M, Haq N, Barnetson RA, Theodoratou E, Cetnarskyj R, Cartwright N, Semple C, Clark AJ, Reid FJ, Smith LA, Kavoussanakis K, Koessler T, Pharoah PD, Buch S, Schafmayer C, Tepel J, Schreiber S, Völzke H, Schmidt CO, Hampe J, Chang-Claude J, Hoffmeister M, Brenner H, Wilkening S, Canzian F, Capella G, Moreno V, Deary IJ, Starr JM, Tomlinson IP, Kemp Z, Howarth K, Carvajal-Carmona L, Webb E, Broderick P, Vijayakrishnan J, Houlston RS, Rennert G, Ballinger D, Rozek L, Gruber SB, Matsuda K, Kidokoro T, Nakamura Y, Zanke BW, Greenwood CM, Rangrej J, Kustra R, Montpetit A, Hudson TJ, Gallinger S, Campbell H, Dunlop MG. Tenesa A, et al. Among authors: deary ij. Nat Genet. 2008 May;40(5):631-7. doi: 10.1038/ng.133. Epub 2008 Mar 30. Nat Genet. 2008. PMID: 18372901 Free PMC article.
Apolipoprotein E is not related to memory abilities at 70 years of age.
Luciano M, Gow AJ, Taylor MD, Hayward C, Harris SE, Campbell H, Porteous DJ, Starr JM, Visscher PM, Deary IJ. Luciano M, et al. Among authors: deary ij. Behav Genet. 2009 Jan;39(1):6-14. doi: 10.1007/s10519-008-9236-x. Epub 2008 Oct 23. Behav Genet. 2009. PMID: 18946731
Association of KIBRA and memory.
Bates TC, Price JF, Harris SE, Marioni RE, Fowkes FG, Stewart MC, Murray GD, Whalley LJ, Starr JM, Deary IJ. Bates TC, et al. Among authors: deary ij. Neurosci Lett. 2009 Jul 24;458(3):140-3. doi: 10.1016/j.neulet.2009.04.050. Epub 2009 May 3. Neurosci Lett. 2009. PMID: 19397951
No association between Cholinergic Muscarinic Receptor 2 (CHRM2) genetic variation and cognitive abilities in three independent samples.
Lind PA, Luciano M, Horan MA, Marioni RE, Wright MJ, Bates TC, Rabbitt P, Harris SE, Davidson Y, Deary IJ, Gibbons L, Pickles A, Ollier W, Pendleton N, Price JF, Payton A, Martin NG. Lind PA, et al. Among authors: deary ij. Behav Genet. 2009 Sep;39(5):513-23. doi: 10.1007/s10519-009-9274-z. Epub 2009 May 6. Behav Genet. 2009. PMID: 19418213
Age-associated cognitive decline.
Deary IJ, Corley J, Gow AJ, Harris SE, Houlihan LM, Marioni RE, Penke L, Rafnsson SB, Starr JM. Deary IJ, et al. Br Med Bull. 2009;92:135-52. doi: 10.1093/bmb/ldp033. Br Med Bull. 2009. PMID: 19776035
Genetic variants associated with altered plasma levels of C-reactive protein are not associated with late-life cognitive ability in four Scottish samples.
Marioni RE, Deary IJ, Murray GD, Lowe GD, Rafnsson SB, Strachan MW, Luciano M, Houlihan LM, Gow AJ, Harris SE, Stewart MC, Rumley A, Fowkes FG, Price JF. Marioni RE, et al. Among authors: deary ij. Behav Genet. 2010 Jan;40(1):3-11. doi: 10.1007/s10519-009-9302-z. Epub 2009 Oct 10. Behav Genet. 2010. PMID: 19821022
1,347 results