Degner J - Search Results

1

A Genetic Variant in the BCL2 Gene Associates with Adalimumab Response in Hidradenitis Suppurativa Clinical Trials and Regulates Expression of BCL2.

Liu M, Degner J, Georgantas RW, Nader A, Mostafa NM, Teixeira HD, Williams DA, Kirsner RS, Nichols AJ, Davis JW, Waring JF. Liu M, et al. Among authors: degner j. J Invest Dermatol. 2020 Mar;140(3):574-582.e2. doi: 10.1016/j.jid.2019.06.152. Epub 2019 Aug 26. J Invest Dermatol. 2020. PMID: 31465739 Free article.

2

Identification of HLA-DRB1 association to adalimumab immunogenicity.

Liu M, Degner J, Davis JW, Idler KB, Nader A, Mostafa NM, Waring JF. Liu M, et al. Among authors: degner j. PLoS One. 2018 Apr 3;13(4):e0195325. doi: 10.1371/journal.pone.0195325. eCollection 2018. PLoS One. 2018. PMID: 29614084 Free PMC article. Clinical Trial.

3

Are drug targets with genetic support twice as likely to be approved? Revised estimates of the impact of genetic support for drug mechanisms on the probability of drug approval.

King EA, Davis JW, Degner JF. King EA, et al. Among authors: degner jf. PLoS Genet. 2019 Dec 12;15(12):e1008489. doi: 10.1371/journal.pgen.1008489. eCollection 2019 Dec. PLoS Genet. 2019. PMID: 31830040 Free PMC article.

4

Estimating colocalization probability from limited summary statistics.

King EA, Dunbar F, Davis JW, Degner JF. King EA, et al. BMC Bioinformatics. 2021 May 17;22(1):254. doi: 10.1186/s12859-021-04170-z. BMC Bioinformatics. 2021. PMID: 34000989 Free PMC article.

5

Population Pharmacokinetics of Elagolix in Combination with Low-Dose Estradiol/Norethindrone Acetate in Women with Uterine Fibroids.

Beck D, Winzenborg I, Liu M, Degner J, Mostafa NM, Noertersheuser P, Shebley M. Beck D, et al. Among authors: degner j. Clin Pharmacokinet. 2022 Apr;61(4):577-587. doi: 10.1007/s40262-021-01096-w. Epub 2021 Dec 8. Clin Pharmacokinet. 2022. PMID: 34878624 Free PMC article.

6

Population Pharmacokinetics of Elagolix in Healthy Women and Women with Endometriosis.

Winzenborg I, Nader A, Polepally AR, Liu M, Degner J, Klein CE, Mostafa NM, Noertersheuser P, Ng J. Winzenborg I, et al. Among authors: degner j. Clin Pharmacokinet. 2018 Oct;57(10):1295-1306. doi: 10.1007/s40262-018-0629-6. Clin Pharmacokinet. 2018. PMID: 29476499

7

DNA methylation patterns associate with genetic and gene expression variation in HapMap cell lines.

Bell JT, Pai AA, Pickrell JK, Gaffney DJ, Pique-Regi R, Degner JF, Gilad Y, Pritchard JK. Bell JT, et al. Among authors: degner jf. Genome Biol. 2011;12(1):R10. doi: 10.1186/gb-2011-12-1-r10. Epub 2011 Jan 20. Genome Biol. 2011. PMID: 21251332 Free PMC article.

8

DNase I sensitivity QTLs are a major determinant of human expression variation.

Degner JF, Pai AA, Pique-Regi R, Veyrieras JB, Gaffney DJ, Pickrell JK, De Leon S, Michelini K, Lewellen N, Crawford GE, Stephens M, Gilad Y, Pritchard JK. Degner JF, et al. Nature. 2012 Feb 5;482(7385):390-4. doi: 10.1038/nature10808. Nature. 2012. PMID: 22307276 Free PMC article.

9

Identification of genetic variants that affect histone modifications in human cells.

McVicker G, van de Geijn B, Degner JF, Cain CE, Banovich NE, Raj A, Lewellen N, Myrthil M, Gilad Y, Pritchard JK. McVicker G, et al. Science. 2013 Nov 8;342(6159):747-9. doi: 10.1126/science.1242429. Epub 2013 Oct 17. Science. 2013. PMID: 24136359 Free PMC article.

10

Methylation QTLs are associated with coordinated changes in transcription factor binding, histone modifications, and gene expression levels.

Banovich NE, Lan X, McVicker G, van de Geijn B, Degner JF, Blischak JD, Roux J, Pritchard JK, Gilad Y. Banovich NE, et al. Among authors: degner jf. PLoS Genet. 2014 Sep 18;10(9):e1004663. doi: 10.1371/journal.pgen.1004663. eCollection 2014 Sep. PLoS Genet. 2014. PMID: 25233095 Free PMC article.

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