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Anti-microbial and cytotoxic 1,6-dihydroxyphenazine-5,10-dioxide (iodinin) produced by Streptosporangium sp. DSM 45942 isolated from the fjord sediment.
Sletta H, Degnes KF, Herfindal L, Klinkenberg G, Fjærvik E, Zahlsen K, Brunsvik A, Nygaard G, Aachmann FL, Ellingsen TE, Døskeland SO, Zotchev SB. Sletta H, et al. Among authors: degnes kf. Appl Microbiol Biotechnol. 2014 Jan;98(2):603-10. doi: 10.1007/s00253-013-5320-0. Epub 2013 Oct 26. Appl Microbiol Biotechnol. 2014. PMID: 24158735
Biosynthesis of macrolactam BE-14106 involves two distinct PKS systems and amino acid processing enzymes for generation of the aminoacyl starter unit.
Jørgensen H, Degnes KF, Sletta H, Fjaervik E, Dikiy A, Herfindal L, Bruheim P, Klinkenberg G, Bredholt H, Nygård G, Døskeland SO, Ellingsen TE, Zotchev SB. Jørgensen H, et al. Among authors: degnes kf. Chem Biol. 2009 Oct 30;16(10):1109-21. doi: 10.1016/j.chembiol.2009.09.014. Chem Biol. 2009. PMID: 19875084
Production of a new thiopeptide antibiotic, TP-1161, by a marine Nocardiopsis species.
Engelhardt K, Degnes KF, Kemmler M, Bredholt H, Fjaervik E, Klinkenberg G, Sletta H, Ellingsen TE, Zotchev SB. Engelhardt K, et al. Among authors: degnes kf. Appl Environ Microbiol. 2010 Aug;76(15):4969-76. doi: 10.1128/AEM.00741-10. Epub 2010 Jun 18. Appl Environ Microbiol. 2010. PMID: 20562278 Free PMC article.
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