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Keratin 18-deficiency results in steatohepatitis and liver tumors in old mice: A model of steatohepatitis-associated liver carcinogenesis.
Bettermann K, Mehta AK, Hofer EM, Wohlrab C, Golob-Schwarzl N, Svendova V, Schimek MG, Stumptner C, Thüringer A, Speicher MR, Lackner C, Zatloukal K, Denk H, Haybaeck J. Bettermann K, et al. Among authors: denk h. Oncotarget. 2016 Nov 8;7(45):73309-73322. doi: 10.18632/oncotarget.12325. Oncotarget. 2016. PMID: 27689336 Free PMC article.
The keratin cytoskeleton in liver diseases.
Zatloukal K, Stumptner C, Fuchsbichler A, Fickert P, Lackner C, Trauner M, Denk H. Zatloukal K, et al. Among authors: denk h. J Pathol. 2004 Nov;204(4):367-76. doi: 10.1002/path.1649. J Pathol. 2004. PMID: 15495250 Review.
Cross β-sheet conformation of keratin 8 is a specific feature of Mallory-Denk bodies compared with other hepatocyte inclusions.
Mahajan V, Klingstedt T, Simon R, Nilsson KP, Thueringer A, Kashofer K, Haybaeck J, Denk H, Abuja PM, Zatloukal K. Mahajan V, et al. Among authors: denk h. Gastroenterology. 2011 Sep;141(3):1080-1090.e1-7. doi: 10.1053/j.gastro.2011.05.039. Epub 2011 May 27. Gastroenterology. 2011. PMID: 21699779
BACKGROUND & AIMS: Mallory-Denk bodies (MDBs) are cytoplasmic protein aggregates in hepatocytes in steatohepatitis and other liver diseases. We investigated the molecular structure of keratin 8 (K8) and 18 (K18), sequestosome 1/p62, and ubiquitin, which are the major c …
BACKGROUND & AIMS: Mallory-Denk bodies (MDBs) are cytoplasmic protein aggregates in hepatocytes in steatohepatitis and other live …
Hepatocellular carcinomas with intracellular hyaline bodies have a poor prognosis.
Aigelsreiter A, Neumann J, Pichler M, Halasz J, Zatloukal K, Berghold A, Douschan P, Rainer F, Stauber R, Haybaeck J, Denk H, Lackner C. Aigelsreiter A, et al. Among authors: denk h. Liver Int. 2017 Apr;37(4):600-610. doi: 10.1111/liv.13325. Epub 2017 Jan 12. Liver Int. 2017. PMID: 27885796
BACKGROUND & AIMS: Mallory-Denk bodies (MDBs) and intracellular hyaline bodies (IHBs) are cytoplasmic inclusions found in a subset of hepatocellular carcinoma (HCC). ...The prognostic impact of inclusions was assessed using Kaplan-Meier and multivariate Cox proportiona …
BACKGROUND & AIMS: Mallory-Denk bodies (MDBs) and intracellular hyaline bodies (IHBs) are cytoplasmic inclusions found in a subse …
Animal models of NAFLD from the pathologist's point of view.
Denk H, Abuja PM, Zatloukal K. Denk H, et al. Biochim Biophys Acta Mol Basis Dis. 2019 May 1;1865(5):929-942. doi: 10.1016/j.bbadis.2018.04.024. Epub 2018 May 8. Biochim Biophys Acta Mol Basis Dis. 2019. PMID: 29746920 Free article. Review.
319 results