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Reformulated tenofovir gel for use as a dual compartment microbicide.
Dezzutti CS, Rohan LC, Wang L, Uranker K, Shetler C, Cost M, Lynam JD, Friend D. Dezzutti CS, et al. J Antimicrob Chemother. 2012 Sep;67(9):2139-42. doi: 10.1093/jac/dks173. Epub 2012 May 11. J Antimicrob Chemother. 2012. PMID: 22581908 Free PMC article.
In vitro and ex vivo testing of tenofovir shows it is effective as an HIV-1 microbicide.
Rohan LC, Moncla BJ, Kunjara Na Ayudhya RP, Cost M, Huang Y, Gai F, Billitto N, Lynam JD, Pryke K, Graebing P, Hopkins N, Rooney JF, Friend D, Dezzutti CS. Rohan LC, et al. Among authors: dezzutti cs. PLoS One. 2010 Feb 19;5(2):e9310. doi: 10.1371/journal.pone.0009310. PLoS One. 2010. PMID: 20174579 Free PMC article.
A Phase 1 Randomized, Open Label, Rectal Safety, Acceptability, Pharmacokinetic, and Pharmacodynamic Study of Three Formulations of Tenofovir 1% Gel (the CHARM-01 Study).
Mcgowan I, Cranston RD, Duffill K, Siegel A, Engstrom JC, Nikiforov A, Jacobson C, Rehman KK, Elliott J, Khanukhova E, Abebe K, Mauck C, Spiegel HM, Dezzutti CS, Rohan LC, Marzinke MA, Hiruy H, Hendrix CW, Richardson-Harman N, Anton PA. Mcgowan I, et al. Among authors: dezzutti cs. PLoS One. 2015 May 5;10(5):e0125363. doi: 10.1371/journal.pone.0125363. eCollection 2015. PLoS One. 2015. PMID: 25942472 Free PMC article. Clinical Trial.
Assessing the potential of the Woman's Condom for vaginal drug delivery.
Kramzer LF, Cohen J, Schubert J, Dezzutti CS, Moncla BJ, Friend D, Rohan LC. Kramzer LF, et al. Among authors: dezzutti cs. Contraception. 2015 Sep;92(3):254-60. doi: 10.1016/j.contraception.2015.05.005. Epub 2015 May 19. Contraception. 2015. PMID: 25998936 Free PMC article.
111 results