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Trans-ethnic analysis of metabochip data identifies two new loci associated with BMI.
Gong J, Nishimura KK, Fernandez-Rhodes L, Haessler J, Bien S, Graff M, Lim U, Lu Y, Gross M, Fornage M, Yoneyama S, Isasi CR, Buzkova P, Daviglus M, Lin DY, Tao R, Goodloe R, Bush WS, Farber-Eger E, Boston J, Dilks HH, Ehret G, Gu CC, Lewis CE, Nguyen KH, Cooper R, Leppert M, Irvin MR, Bottinger EP, Wilkens LR, Haiman CA, Park L, Monroe KR, Cheng I, Stram DO, Carlson CS, Jackson R, Kuller L, Houston D, Kooperberg C, Buyske S, Hindorff LA, Crawford DC, Loos RJF, Le Marchand L, Matise TC, North KE, Peters U. Gong J, et al. Among authors: dilks hh. Int J Obes (Lond). 2018 Mar;42(3):384-390. doi: 10.1038/ijo.2017.304. Epub 2017 Dec 21. Int J Obes (Lond). 2018. PMID: 29381148 Free PMC article.
Detection of pleiotropy through a Phenome-wide association study (PheWAS) of epidemiologic data as part of the Environmental Architecture for Genes Linked to Environment (EAGLE) study.
Hall MA, Verma A, Brown-Gentry KD, Goodloe R, Boston J, Wilson S, McClellan B, Sutcliffe C, Dilks HH, Gillani NB, Jin H, Mayo P, Allen M, Schnetz-Boutaud N, Crawford DC, Ritchie MD, Pendergrass SA. Hall MA, et al. Among authors: dilks hh. PLoS Genet. 2014 Dec 4;10(12):e1004678. doi: 10.1371/journal.pgen.1004678. eCollection 2014 Dec. PLoS Genet. 2014. PMID: 25474351 Free PMC article.
Evidence for extensive pleiotropy among pharmacogenes.
Oetjens MT, Bush WS, Denny JC, Birdwell K, Kodaman N, Verma A, Dilks HH, Pendergrass SA, Ritchie MD, Crawford DC. Oetjens MT, et al. Among authors: dilks hh. Pharmacogenomics. 2016 Jun;17(8):853-66. doi: 10.2217/pgs-2015-0007. Epub 2016 Jun 1. Pharmacogenomics. 2016. PMID: 27249515 Free PMC article.
Pleiotropic and sex-specific effects of cancer GWAS SNPs on melanoma risk in the population architecture using genomics and epidemiology (PAGE) study.
Kocarnik JM, Park SL, Han J, Dumitrescu L, Cheng I, Wilkens LR, Schumacher FR, Kolonel L, Carlson CS, Crawford DC, Goodloe RJ, Dilks HH, Baker P, Richardson D, Matise TC, Ambite JL, Song F, Qureshi AA, Zhang M, Duggan D, Hutter C, Hindorff L, Bush WS, Kooperberg C, Le Marchand L, Peters U. Kocarnik JM, et al. Among authors: dilks hh. PLoS One. 2015 Mar 19;10(3):e0120491. doi: 10.1371/journal.pone.0120491. eCollection 2015. PLoS One. 2015. PMID: 25789475 Free PMC article.
Replication of SCN5A Associations with Electrocardio-graphic Traits in African Americans from Clinical and Epidemiologic Studies.
Jeff JM, Brown-Gentry K, Goodloe R, Ritchie MD, Denny JC, Kho AN, Armstrong LL, McClellan B Jr, Mayo P, Allen M, Jin H, Gillani NB, Schnetz-Boutaud N, Dilks HH, Basford MA, Pacheco JA, Jarvik GP, Chisholm RL, Roden DM, Hayes MG, Crawford DC. Jeff JM, et al. Among authors: dilks hh. Evol Comput Mach Learn Data Min Bioinform. 2014;2014:939-951. doi: 10.1007/978-3-662-45523-4_76. Evol Comput Mach Learn Data Min Bioinform. 2014. PMID: 25590050 Free PMC article.
GWATCH: a web platform for automated gene association discovery analysis.
Svitin A, Malov S, Cherkasov N, Geerts P, Rotkevich M, Dobrynin P, Shevchenko A, Guan L, Troyer J, Hendrickson S, Dilks HH, Oleksyk TK, Donfield S, Gomperts E, Jabs DA, Sezgin E, Van Natta M, Harrigan PR, Brumme ZL, O'Brien SJ. Svitin A, et al. Among authors: dilks hh. Gigascience. 2014 Nov 5;3:18. doi: 10.1186/2047-217X-3-18. eCollection 2014. Gigascience. 2014. PMID: 25374661 Free PMC article.
Rare variant APOC3 R19X is associated with cardio-protective profiles in a diverse population-based survey as part of the Epidemiologic Architecture for Genes Linked to Environment Study.
Crawford DC, Dumitrescu L, Goodloe R, Brown-Gentry K, Boston J, McClellan B Jr, Sutcliffe C, Wiseman R, Baker P, Pericak-Vance MA, Scott WK, Allen M, Mayo P, Schnetz-Boutaud N, Dilks HH, Haines JL, Pollin TI. Crawford DC, et al. Among authors: dilks hh. Circ Cardiovasc Genet. 2014 Dec;7(6):848-53. doi: 10.1161/CIRCGENETICS.113.000369. Epub 2014 Nov 1. Circ Cardiovasc Genet. 2014. PMID: 25363704 Free PMC article.
22 results