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TRAIL induces necroptosis involving RIPK1/RIPK3-dependent PARP-1 activation.
Jouan-Lanhouet S, Arshad MI, Piquet-Pellorce C, Martin-Chouly C, Le Moigne-Muller G, Van Herreweghe F, Takahashi N, Sergent O, Lagadic-Gossmann D, Vandenabeele P, Samson M, Dimanche-Boitrel MT. Jouan-Lanhouet S, et al. Cell Death Differ. 2012 Dec;19(12):2003-14. doi: 10.1038/cdd.2012.90. Epub 2012 Jul 20. Cell Death Differ. 2012. PMID: 22814620 Free PMC article.
A Transversal Approach Combining In Silico, In Vitro and In Vivo Models to Describe the Metabolism of the Receptor Interacting Protein 1 Kinase Inhibitor Sibiriline.
Pelletier R, Gicquel T, Simoes Eugenio M, Ferron PJ, Morel I, Delehouzé C, Dimanche-Boitrel MT, Rousselot M, Le Daré B. Pelletier R, et al. Among authors: dimanche boitrel mt. Pharmaceutics. 2022 Nov 30;14(12):2665. doi: 10.3390/pharmaceutics14122665. Pharmaceutics. 2022. PMID: 36559159 Free PMC article.
Receptor-interacting protein kinase-1 ablation in liver parenchymal cells promotes liver fibrosis in murine NASH without affecting other symptoms.
Farooq M, Simoes Eugénio M, Piquet-Pellorce C, Dion S, Raguenes-Nicol C, Santamaria K, Kara-Ali GH, Larcher T, Dimanche-Boitrel MT, Samson M, Le Seyec J. Farooq M, et al. Among authors: dimanche boitrel mt. J Mol Med (Berl). 2022 Jul;100(7):1027-1038. doi: 10.1007/s00109-022-02192-5. Epub 2022 Apr 27. J Mol Med (Berl). 2022. PMID: 35476028 Free article.
Nigratine as dual inhibitor of necroptosis and ferroptosis regulated cell death.
Delehouzé C, Comte A, Leon-Icaza SA, Cougoule C, Hauteville M, Goekjian P, Bulinski JC, Dimanche-Boitrel MT, Meunier E, Rousselot M, Bach S. Delehouzé C, et al. Among authors: dimanche boitrel mt. Sci Rep. 2022 Mar 24;12(1):5118. doi: 10.1038/s41598-022-09019-w. Sci Rep. 2022. PMID: 35332201 Free PMC article.
Betulin, a Newly Characterized Compound in Acacia auriculiformis Bark, Is a Multi-Target Protein Kinase Inhibitor.
Ahmadu AA, Delehouzé C, Haruna A, Mustapha L, Lawal BA, Udobre A, Baratte B, Triscornia C, Autret A, Robert T, Bulinski JC, Rousselot M, Simoes Eugénio M, Dimanche-Boitrel MT, Petzer JP, Legoabe LJ, Bach S. Ahmadu AA, et al. Among authors: dimanche boitrel mt. Molecules. 2021 Jul 29;26(15):4599. doi: 10.3390/molecules26154599. Molecules. 2021. PMID: 34361750 Free PMC article.
TRIM21, a New Component of the TRAIL-Induced Endogenous Necrosome Complex.
Simoes Eugénio M, Faurez F, Kara-Ali GH, Lagarrigue M, Uhart P, Bonnet MC, Gallais I, Com E, Pineau C, Samson M, Le Seyec J, Dimanche-Boitrel MT. Simoes Eugénio M, et al. Among authors: dimanche boitrel mt. Front Mol Biosci. 2021 Apr 15;8:645134. doi: 10.3389/fmolb.2021.645134. eCollection 2021. Front Mol Biosci. 2021. PMID: 33937329 Free PMC article.
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