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Vaginally administered PEGylated LIF antagonist blocked embryo implantation and eliminated non-target effects on bone in mice.
Menkhorst E, Zhang JG, Sims NA, Morgan PO, Soo P, Poulton IJ, Metcalf D, Alexandrou E, Gresle M, Salamonsen LA, Butzkueven H, Nicola NA, Dimitriadis E. Menkhorst E, et al. Among authors: dimitriadis e. PLoS One. 2011;6(5):e19665. doi: 10.1371/journal.pone.0019665. Epub 2011 May 18. PLoS One. 2011. PMID: 21611124 Free PMC article.
Polyethylene glycated leukemia inhibitory factor antagonist inhibits human blastocyst implantation and triggers apoptosis by down-regulating embryonic AKT.
Lalitkumar S, Boggavarapu NR, Menezes J, Dimitriadis E, Zhang JG, Nicola NA, Gemzell-Danielsson K, Lalitkumar LP. Lalitkumar S, et al. Among authors: dimitriadis e. Fertil Steril. 2013 Oct;100(4):1160-9. doi: 10.1016/j.fertnstert.2013.06.023. Epub 2013 Jul 19. Fertil Steril. 2013. PMID: 23876532 Free article.
Interleukin-11 alters placentation and causes preeclampsia features in mice.
Winship AL, Koga K, Menkhorst E, Van Sinderen M, Rainczuk K, Nagai M, Cuman C, Yap J, Zhang JG, Simmons D, Young MJ, Dimitriadis E. Winship AL, et al. Among authors: dimitriadis e. Proc Natl Acad Sci U S A. 2015 Dec 29;112(52):15928-33. doi: 10.1073/pnas.1515076112. Epub 2015 Dec 11. Proc Natl Acad Sci U S A. 2015. PMID: 26655736 Free PMC article.
The role of leukemia inhibitory factor in tubal ectopic pregnancy.
Krishnan T, Winship A, Sonderegger S, Menkhorst E, Horne AW, Brown J, Zhang JG, Nicola NA, Tong S, Dimitriadis E. Krishnan T, et al. Among authors: dimitriadis e. Placenta. 2013 Nov;34(11):1014-9. doi: 10.1016/j.placenta.2013.09.003. Epub 2013 Sep 13. Placenta. 2013. PMID: 24074901
IL11 activates the placental inflammasome to drive preeclampsia.
Menkhorst E, Santos LL, Zhou W, Yang G, Winship AL, Rainczuk KE, Nguyen P, Zhang JG, Moore P, Williams M, Lê Cao KA, Mansell A, Dimitriadis E. Menkhorst E, et al. Among authors: dimitriadis e. Front Immunol. 2023 May 24;14:1175926. doi: 10.3389/fimmu.2023.1175926. eCollection 2023. Front Immunol. 2023. PMID: 37292200 Free PMC article.
240 results