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Identification of orally available naphthyridine protein kinase D inhibitors.
J Med Chem. 2010 Aug 12;53(15):5400-21. doi: 10.1021/jm100075z.
J Med Chem. 2010.
PMID: 20684591
Human HDAC isoform selectivity achieved via exploitation of the acetate release channel with structurally unique small molecule inhibitors.
Whitehead L, Dobler MR, Radetich B, Zhu Y, Atadja PW, Claiborne T, Grob JE, McRiner A, Pancost MR, Patnaik A, Shao W, Shultz M, Tichkule R, Tommasi RA, Vash B, Wang P, Stams T.
Whitehead L, et al. Among authors: dobler mr.
Bioorg Med Chem. 2011 Aug 1;19(15):4626-34. doi: 10.1016/j.bmc.2011.06.030. Epub 2011 Jun 15.
Bioorg Med Chem. 2011.
PMID: 21723733
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2-Alkyloxazoles as potent and selective PI4KIIIβ inhibitors demonstrating inhibition of HCV replication.
Keaney EP, Connolly M, Dobler M, Karki R, Honda A, Sokup S, Karur S, Britt S, Patnaik A, Raman P, Hamann LG, Wiedmann B, LaMarche MJ.
Keaney EP, et al.
Bioorg Med Chem Lett. 2014 Aug 15;24(16):3714-8. doi: 10.1016/j.bmcl.2014.07.015. Epub 2014 Jul 12.
Bioorg Med Chem Lett. 2014.
PMID: 25065492
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Design, Synthesis, and Properties of a Potent Inhibitor of Pseudomonas aeruginosa Deacetylase LpxC.
Piizzi G, Parker DT, Peng Y, Dobler M, Patnaik A, Wattanasin S, Liu E, Lenoir F, Nunez J, Kerrigan J, McKenney D, Osborne C, Yu D, Lanieri L, Bojkovic J, Dzink-Fox J, Lilly MD, Sprague ER, Lu Y, Wang H, Ranjitkar S, Xie L, Wang B, Glick M, Hamann LG, Tommasi R, Yang X, Dean CR.
Piizzi G, et al.
J Med Chem. 2017 Jun 22;60(12):5002-5014. doi: 10.1021/acs.jmedchem.7b00377. Epub 2017 Jun 9.
J Med Chem. 2017.
PMID: 28549219
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Anti-hepatitis C virus activity and toxicity of type III phosphatidylinositol-4-kinase beta inhibitors.
Lamarche MJ, Borawski J, Bose A, Capacci-Daniel C, Colvin R, Dennehy M, Ding J, Dobler M, Drumm J, Gaither LA, Gao J, Jiang X, Lin K, McKeever U, Puyang X, Raman P, Thohan S, Tommasi R, Wagner K, Xiong X, Zabawa T, Zhu S, Wiedmann B.
Lamarche MJ, et al.
Antimicrob Agents Chemother. 2012 Oct;56(10):5149-56. doi: 10.1128/AAC.00946-12. Epub 2012 Jul 23.
Antimicrob Agents Chemother. 2012.
PMID: 22825118
Free PMC article.
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Investigating the Structure-Activity Relationship of the Insecticidal Natural Product Rocaglamide.
Hall RG, Bruce I, Cooke NG, Diorazio LJ, Cederbaum F, Dobler MR, Irving E.
Hall RG, et al. Among authors: dobler mr.
Chimia (Aarau). 2017 Dec 1;71(12):845-850. doi: 10.2533/chimia.2017.845.
Chimia (Aarau). 2017.
PMID: 29289246
Free article.
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Synthesis and fungicidal activity of tubulin polymerisation promoters. Part 1: pyrido[2,3-b]pyrazines.
Crowley PJ, Lamberth C, Müller U, Wendeborn S, Nebel K, Williams J, Sageot OA, Carter N, Mathie T, Kempf HJ, Godwin J, Schneiter P, Dobler MR.
Crowley PJ, et al. Among authors: dobler mr.
Pest Manag Sci. 2010 Feb;66(2):178-85. doi: 10.1002/ps.1852.
Pest Manag Sci. 2010.
PMID: 19795441
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A short and efficient preparation of methyl-[1,2,4]oxadiazolium derivatives with plant-inducing activity.
Dobler MR.
Dobler MR.
Org Biomol Chem. 2004 Apr 7;2(7):963-4. doi: 10.1039/b316802f. Epub 2004 Feb 26.
Org Biomol Chem. 2004.
PMID: 15034617
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