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The chaperone HSPB8 reduces the accumulation of truncated TDP-43 species in cells and protects against TDP-43-mediated toxicity.
Crippa V, Cicardi ME, Ramesh N, Seguin SJ, Ganassi M, Bigi I, Diacci C, Zelotti E, Baratashvili M, Gregory JM, Dobson CM, Cereda C, Pandey UB, Poletti A, Carra S. Crippa V, et al. Among authors: dobson cm. Hum Mol Genet. 2016 Sep 15;25(18):3908-3924. doi: 10.1093/hmg/ddw232. Epub 2016 Jul 27. Hum Mol Genet. 2016. PMID: 27466192 Free PMC article.
Dynamics and timekeeping in biological systems.
Dobson CM. Dobson CM. Annu Rev Biochem. 2014;83:159-64. doi: 10.1146/annurev-biochem-013014-102724. Epub 2014 Mar 3. Annu Rev Biochem. 2014. PMID: 24606145
Chemical space and biology.
Dobson CM. Dobson CM. Nature. 2004 Dec 16;432(7019):824-8. doi: 10.1038/nature03192. Nature. 2004. PMID: 15602547
Structure-Toxicity Relationship in Intermediate Fibrils from α-Synuclein Condensates.
Chen SW, Barritt JD, Cascella R, Bigi A, Cecchi C, Banchelli M, Gallo A, Jarvis JA, Chiti F, Dobson CM, Fusco G, De Simone A. Chen SW, et al. Among authors: dobson cm. J Am Chem Soc. 2024 Apr 17;146(15):10537-10549. doi: 10.1021/jacs.3c14703. Epub 2024 Apr 3. J Am Chem Soc. 2024. PMID: 38567991 Free PMC article.
N-Terminal Acetylation of α-Synuclein Slows down Its Aggregation Process and Alters the Morphology of the Resulting Aggregates.
Bell R, Thrush RJ, Castellana-Cruz M, Oeller M, Staats R, Nene A, Flagmeier P, Xu CK, Satapathy S, Galvagnion C, Wilson MR, Dobson CM, Kumita JR, Vendruscolo M. Bell R, et al. Among authors: dobson cm. Biochemistry. 2022 Sep 6;61(17):1743-1756. doi: 10.1021/acs.biochem.2c00104. Epub 2022 Aug 9. Biochemistry. 2022. PMID: 35944093 Free PMC article.
803 results