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Human XCR1+ dendritic cells derived in vitro from CD34+ progenitors closely resemble blood dendritic cells, including their adjuvant responsiveness, contrary to monocyte-derived dendritic cells.
Balan S, Ollion V, Colletti N, Chelbi R, Montanana-Sanchis F, Liu H, Vu Manh TP, Sanchez C, Savoret J, Perrot I, Doffin AC, Fossum E, Bechlian D, Chabannon C, Bogen B, Asselin-Paturel C, Shaw M, Soos T, Caux C, Valladeau-Guilemond J, Dalod M. Balan S, et al. Among authors: doffin ac. J Immunol. 2014 Aug 15;193(4):1622-35. doi: 10.4049/jimmunol.1401243. Epub 2014 Jul 9. J Immunol. 2014. PMID: 25009205 Free PMC article.
Regulatory T cells recruited through CCL22/CCR4 are selectively activated in lymphoid infiltrates surrounding primary breast tumors and lead to an adverse clinical outcome.
Gobert M, Treilleux I, Bendriss-Vermare N, Bachelot T, Goddard-Leon S, Arfi V, Biota C, Doffin AC, Durand I, Olive D, Perez S, Pasqual N, Faure C, Ray-Coquard I, Puisieux A, Caux C, Blay JY, Ménétrier-Caux C. Gobert M, et al. Among authors: doffin ac. Cancer Res. 2009 Mar 1;69(5):2000-9. doi: 10.1158/0008-5472.CAN-08-2360. Epub 2009 Feb 24. Cancer Res. 2009. PMID: 19244125
Human natural killer cells promote cross-presentation of tumor cell-derived antigens by dendritic cells.
Deauvieau F, Ollion V, Doffin AC, Achard C, Fonteneau JF, Verronese E, Durand I, Ghittoni R, Marvel J, Dezutter-Dambuyant C, Walzer T, Vie H, Perrot I, Goutagny N, Caux C, Valladeau-Guilemond J. Deauvieau F, et al. Among authors: doffin ac. Int J Cancer. 2015 Mar 1;136(5):1085-94. doi: 10.1002/ijc.29087. Epub 2014 Aug 6. Int J Cancer. 2015. PMID: 25046660 Free article.
IFN-III is selectively produced by cDC1 and predicts good clinical outcome in breast cancer.
Hubert M, Gobbini E, Couillault C, Manh TV, Doffin AC, Berthet J, Rodriguez C, Ollion V, Kielbassa J, Sajous C, Treilleux I, Tredan O, Dubois B, Dalod M, Bendriss-Vermare N, Caux C, Valladeau-Guilemond J. Hubert M, et al. Among authors: doffin ac. Sci Immunol. 2020 Apr 17;5(46):eaav3942. doi: 10.1126/sciimmunol.aav3942. Epub 2020 Apr 17. Sci Immunol. 2020. PMID: 32303573
Guidelines for visualization and analysis of DC in tissues using multiparameter fluorescence microscopy imaging methods.
Bayerl F, Bejarano DA, Bertacchi G, Doffin AC, Gobbini E, Hubert M, Li L, Meiser P, Pedde AM, Posch W, Rupp L, Schlitzer A, Schmitz M, Schraml BU, Uderhardt S, Valladeau-Guilemond J, Wilflingseder D, Zaderer V, Böttcher JP. Bayerl F, et al. Among authors: doffin ac. Eur J Immunol. 2023 Nov;53(11):e2249923. doi: 10.1002/eji.202249923. Epub 2023 Jan 9. Eur J Immunol. 2023. PMID: 36623939