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Pharmacokinetics and efficacy of topical inserts containing tenofovir alafenamide fumarate and elvitegravir administered rectally in macaques.
Makarova N, Singletary T, Peet MM, Mitchell J, Holder A, Dinh C, Agrahari V, Mendoza M, Pan Y, Heneine W, Clark MR, García-Lerma JG, Smith JM, Doncel GF. Makarova N, et al. Among authors: doncel gf. EBioMedicine. 2022 Dec;86:104338. doi: 10.1016/j.ebiom.2022.104338. Epub 2022 Nov 5. EBioMedicine. 2022. PMID: 36343572 Free PMC article.
Single dose topical inserts containing tenofovir alafenamide fumarate and elvitegravir provide pre- and post-exposure protection against vaginal SHIV infection in macaques.
Dobard CW, Peet MM, Nishiura K, Holder A, Dinh C, Mitchell J, Khalil G, Pan Y, Singh ON, McCormick TJ, Agrahari V, Gupta P, Jonnalagadda S, Heneine W, Clark MR, García-Lerma JG, Doncel GF. Dobard CW, et al. Among authors: doncel gf. EBioMedicine. 2022 Dec;86:104361. doi: 10.1016/j.ebiom.2022.104361. Epub 2022 Nov 21. EBioMedicine. 2022. PMID: 36423375 Free PMC article.
Extended post-exposure protection against vaginal SHIV infection with tenofovir alafenamide fumarate/elvitegravir inserts in macaques.
Makarova N, Singletary T, Peet MM, Mitchell J, Bachman S, Holder A, Dinh C, Lipscomb J, Agrahari V, Mendoza M, Pan Y, Heneine W, Clark MR, García-Lerma JG, Doncel GF, Smith JM. Makarova N, et al. Among authors: doncel gf. J Infect Dis. 2023 Dec 22:jiad599. doi: 10.1093/infdis/jiad599. Online ahead of print. J Infect Dis. 2023. PMID: 38134382
A Phase 1 Clinical Trial to Assess the Safety and Pharmacokinetics of a Tenofovir Alafenamide/Elvitegravir Insert Administered Rectally for HIV Prevention.
Riddler SA, Kelly CW, Hoesley CJ, Ho KS, Piper JM, Edick S, Heard F, Doncel GF, Johnson S, Anderson PL, Brand RM, Kunjara Na Ayudhya RP, Bauermeister JA, Hillier SL, Hendrix CW. Riddler SA, et al. Among authors: doncel gf. J Infect Dis. 2024 Apr 24:jiae211. doi: 10.1093/infdis/jiae211. Online ahead of print. J Infect Dis. 2024. PMID: 38655842
History of Rectal Product Use and Country of Residence Influence Preference for Rectal Microbicide Dosage Forms Among Young Sexual and Gender Minorities: A Multi-country Trial Comparing Placebo Douche, Suppository, and Insert Products.
Giguere R, Balán IC, Kutner BA, Choi SK, Tingler R, Johnson S, Macagna N, Webster J, Liu A, Chariyalertsak S, Hoesley C, Gonzales P, Ho K, Kayange N, Palanee-Phillips T, Brown E, Zemanek J, Jacobson CE, Doncel GF, Piper J, Bauermeister JA; MTN-035 Protocol Team. Giguere R, et al. Among authors: doncel gf. AIDS Behav. 2024 May 13. doi: 10.1007/s10461-024-04360-9. Online ahead of print. AIDS Behav. 2024. PMID: 38740628
174 results