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Treatment of metastatic melanoma using interleukin-2 alone or in conjunction with vaccines.
Clin Cancer Res. 2008 Sep 1;14(17):5610-8. doi: 10.1158/1078-0432.CCR-08-0116.
Clin Cancer Res. 2008.
PMID: 18765555
Free PMC article.
Prognostic factors related to clinical response in patients with metastatic melanoma treated by CTL-associated antigen-4 blockade.
Downey SG, Klapper JA, Smith FO, Yang JC, Sherry RM, Royal RE, Kammula US, Hughes MS, Allen TE, Levy CL, Yellin M, Nichol G, White DE, Steinberg SM, Rosenberg SA.
Downey SG, et al.
Clin Cancer Res. 2007 Nov 15;13(22 Pt 1):6681-8. doi: 10.1158/1078-0432.CCR-07-0187. Epub 2007 Nov 2.
Clin Cancer Res. 2007.
PMID: 17982122
Free PMC article.
Clinical Trial.
Item in Clipboard
High-dose interleukin-2 for the treatment of metastatic renal cell carcinoma : a retrospective analysis of response and survival in patients treated in the surgery branch at the National Cancer Institute between 1986 and 2006.
Klapper JA, Downey SG, Smith FO, Yang JC, Hughes MS, Kammula US, Sherry RM, Royal RE, Steinberg SM, Rosenberg S.
Klapper JA, et al. Among authors: downey sg.
Cancer. 2008 Jul 15;113(2):293-301. doi: 10.1002/cncr.23552.
Cancer. 2008.
PMID: 18457330
Free PMC article.
Item in Clipboard
Adoptive cell therapy for patients with metastatic melanoma: evaluation of intensive myeloablative chemoradiation preparative regimens.
Dudley ME, Yang JC, Sherry R, Hughes MS, Royal R, Kammula U, Robbins PF, Huang J, Citrin DE, Leitman SF, Wunderlich J, Restifo NP, Thomasian A, Downey SG, Smith FO, Klapper J, Morton K, Laurencot C, White DE, Rosenberg SA.
Dudley ME, et al. Among authors: downey sg.
J Clin Oncol. 2008 Nov 10;26(32):5233-9. doi: 10.1200/JCO.2008.16.5449. Epub 2008 Sep 22.
J Clin Oncol. 2008.
PMID: 18809613
Free PMC article.
Clinical Trial.
Item in Clipboard
Adoptive cell therapy for patients with melanoma, using tumor-infiltrating lymphocytes genetically engineered to secrete interleukin-2.
Heemskerk B, Liu K, Dudley ME, Johnson LA, Kaiser A, Downey S, Zheng Z, Shelton TE, Matsuda K, Robbins PF, Morgan RA, Rosenberg SA.
Heemskerk B, et al.
Hum Gene Ther. 2008 May;19(5):496-510. doi: 10.1089/hum.2007.0171.
Hum Gene Ther. 2008.
PMID: 18444786
Free PMC article.
Clinical Trial.
Item in Clipboard
Recognition of NY-ESO-1+ tumor cells by engineered lymphocytes is enhanced by improved vector design and epigenetic modulation of tumor antigen expression.
Wargo JA, Robbins PF, Li Y, Zhao Y, El-Gamil M, Caragacianu D, Zheng Z, Hong JA, Downey S, Schrump DS, Rosenberg SA, Morgan RA.
Wargo JA, et al.
Cancer Immunol Immunother. 2009 Mar;58(3):383-94. doi: 10.1007/s00262-008-0562-x. Epub 2008 Aug 2.
Cancer Immunol Immunother. 2009.
PMID: 18677478
Free PMC article.
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