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Exome sequencing of 20,791 cases of type 2 diabetes and 24,440 controls.
Flannick J, Mercader JM, Fuchsberger C, Udler MS, Mahajan A, Wessel J, Teslovich TM, Caulkins L, Koesterer R, Barajas-Olmos F, Blackwell TW, Boerwinkle E, Brody JA, Centeno-Cruz F, Chen L, Chen S, Contreras-Cubas C, Córdova E, Correa A, Cortes M, DeFronzo RA, Dolan L, Drews KL, Elliott A, Floyd JS, Gabriel S, Garay-Sevilla ME, García-Ortiz H, Gross M, Han S, Heard-Costa NL, Jackson AU, Jørgensen ME, Kang HM, Kelsey M, Kim BJ, Koistinen HA, Kuusisto J, Leader JB, Linneberg A, Liu CT, Liu J, Lyssenko V, Manning AK, Marcketta A, Malacara-Hernandez JM, Martínez-Hernández A, Matsuo K, Mayer-Davis E, Mendoza-Caamal E, Mohlke KL, Morrison AC, Ndungu A, Ng MCY, O'Dushlaine C, Payne AJ, Pihoker C; Broad Genomics Platform; Post WS, Preuss M, Psaty BM, Vasan RS, Rayner NW, Reiner AP, Revilla-Monsalve C, Robertson NR, Santoro N, Schurmann C, So WY, Soberón X, Stringham HM, Strom TM, Tam CHT, Thameem F, Tomlinson B, Torres JM, Tracy RP, van Dam RM, Vujkovic M, Wang S, Welch RP, Witte DR, Wong TY, Atzmon G, Barzilai N, Blangero J, Bonnycastle LL, Bowden DW, Chambers JC, Chan E, Cheng CY, Cho YS, Collins FS, de Vries PS, Duggirala R, Glaser B, Gonzalez C, Gonzalez ME, Groop L, Kooner JS, … See abstract for full author list ➔ Flannick J, et al. Among authors: drews kl. Nature. 2019 Jun;570(7759):71-76. doi: 10.1038/s41586-019-1231-2. Epub 2019 May 22. Nature. 2019. PMID: 31118516 Free PMC article.
ZnT8 autoantibody prevalence is low in youth with type 2 diabetes and associated with higher insulin sensitivity, lower insulin secretion, and lower disposition index.
Higgins J, Zeitler P, Drews KL, Arslanian S, Copeland K, Goland R, Klingensmith G, Lipman TH, Tollefsen S; TODAY Study Group. Higgins J, et al. Among authors: drews kl. J Clin Transl Endocrinol. 2022 May 11;29:100300. doi: 10.1016/j.jcte.2022.100300. eCollection 2022 Sep. J Clin Transl Endocrinol. 2022. PMID: 35601597 Free PMC article.
Diabetes Care Barriers, Use, and Health Outcomes in Younger Adults With Type 1 and Type 2 Diabetes.
Pihoker C, Braffett BH, Songer TJ, Herman WH, Tung M, Kuo S, Bellatorre A, Isganaitis E, Jensen ET, Divers J, Zhang P, Nathan DM, Drews K, Dabelea D, Zeitler PS; Writing Committee for the SEARCH for Diabetes in Youth Study Group and the TODAY Study Group. Pihoker C, et al. JAMA Netw Open. 2023 May 1;6(5):e2312147. doi: 10.1001/jamanetworkopen.2023.12147. JAMA Netw Open. 2023. PMID: 37145592 Free PMC article. Clinical Trial.
Long-Term Complications in Youth-Onset Type 2 Diabetes.
TODAY Study Group; Bjornstad P, Drews KL, Caprio S, Gubitosi-Klug R, Nathan DM, Tesfaldet B, Tryggestad J, White NH, Zeitler P. TODAY Study Group, et al. Among authors: drews kl. N Engl J Med. 2021 Jul 29;385(5):416-426. doi: 10.1056/NEJMoa2100165. N Engl J Med. 2021. PMID: 34320286 Free PMC article.
Major adverse events in youth-onset type 1 and type 2 diabetes: The SEARCH and TODAY studies.
Mottl AK, Tryggestad JB, Isom S, Gubitosi-Klug RA, Henkin L, White NH, D'Agostino R Jr, Hughan KS, Dolan LM, Drews KL; SEARCH for Diabetes in Youth Study Group; TODAY Study Group. Mottl AK, et al. Among authors: drews kl. Diabetes Res Clin Pract. 2024 Apr;210:111606. doi: 10.1016/j.diabres.2024.111606. Epub 2024 Mar 15. Diabetes Res Clin Pract. 2024. PMID: 38493952
41 results