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Insulin receptor substrate 2 is a negative regulator of memory formation.
Irvine EE, Drinkwater L, Radwanska K, Al-Qassab H, Smith MA, O'Brien M, Kielar C, Choudhury AI, Krauss S, Cooper JD, Withers DJ, Giese KP. Irvine EE, et al. Among authors: drinkwater l. Learn Mem. 2011 May 19;18(6):375-83. doi: 10.1101/lm.2111311. Print 2011 Jun. Learn Mem. 2011. PMID: 21597043 Free PMC article.
Deletion of Irs2 reduces amyloid deposition and rescues behavioural deficits in APP transgenic mice.
Killick R, Scales G, Leroy K, Causevic M, Hooper C, Irvine EE, Choudhury AI, Drinkwater L, Kerr F, Al-Qassab H, Stephenson J, Yilmaz Z, Giese KP, Brion JP, Withers DJ, Lovestone S. Killick R, et al. Among authors: drinkwater l. Biochem Biophys Res Commun. 2009 Aug 14;386(1):257-62. doi: 10.1016/j.bbrc.2009.06.032. Epub 2009 Jun 10. Biochem Biophys Res Commun. 2009. PMID: 19523444 Free PMC article.
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