The inference of stepwise changes in substitution rates using serial sequence samples.
Drummond A, Forsberg R, Rodrigo AG.
Drummond A, et al.
Mol Biol Evol. 2001 Jul;18(7):1365-71. doi: 10.1093/oxfordjournals.molbev.a003920.
Mol Biol Evol. 2001.
PMID: 11420374
The first is an extension of the phylogeny-based maximum-likelihood estimation procedure introduced by Rambaut. The second is a new parameterization of the pairwise distance least-squares procedure used by Drummond and Rodrigo. The utility of these methods is demons …
The first is an extension of the phylogeny-based maximum-likelihood estimation procedure introduced by Rambaut. The second is a new p …