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Showing results for dumanski mo
Search for Duzanski MO instead (1 results)
Women, lipids, and atherosclerotic cardiovascular disease: a call to action from the European Atherosclerosis Society.
Roeters van Lennep JE, Tokgözoğlu LS, Badimon L, Dumanski SM, Gulati M, Hess CN, Holven KB, Kavousi M, Kayıkçıoğlu M, Lutgens E, Michos ED, Prescott E, Stock JK, Tybjaerg-Hansen A, Wermer MJH, Benn M. Roeters van Lennep JE, et al. Eur Heart J. 2023 Oct 14;44(39):4157-4173. doi: 10.1093/eurheartj/ehad472. Eur Heart J. 2023. PMID: 37611089 Free PMC article.
Cardiovascular disease is the leading cause of death in women and men globally, with most due to atherosclerotic cardiovascular disease (ASCVD). Despite progress during the last 30 years, ASCVD mortality is now increasing, with the fastest relative increase in middle-aged …
Cardiovascular disease is the leading cause of death in women and men globally, with most due to atherosclerotic cardiovascular disease (ASC …
Evaluation and Management of Hypertensive Disorders of Pregnancy.
Bajpai D, Popa C, Verma P, Dumanski S, Shah S. Bajpai D, et al. Kidney360. 2023 Oct 1;4(10):1512-1525. doi: 10.34067/KID.0000000000000228. Kidney360. 2023. PMID: 37526641 Free PMC article. Review.
Hypertensive disorders of pregnancy complicate up to 10% of pregnancies and remain the major cause of maternal and neonatal morbidity and mortality. Hypertensive disorders of pregnancy can be classified into four groups depending on the onset of hypertension and the presen …
Hypertensive disorders of pregnancy complicate up to 10% of pregnancies and remain the major cause of maternal and neonatal morbidity and …
Improving the inclusion of transgender and nonbinary individuals in the planning, completion, and mobilization of cardiovascular research.
Rytz CL, Beach LB, Saad N, Dumanski SM, Collister D, Newbert AM, Peace L, Lett E, Greene D, Connelly P, Veale J, Morillo C, Ahmed SB. Rytz CL, et al. Am J Physiol Heart Circ Physiol. 2023 Mar 1;324(3):H366-H372. doi: 10.1152/ajpheart.00494.2022. Epub 2023 Jan 13. Am J Physiol Heart Circ Physiol. 2023. PMID: 36637972 Free article.
Cardiovascular disease is the leading cause of morbidity and mortality globally. Transgender and nonbinary (TNB) individuals face unclear but potentially significant cardiovascular health inequities, yet no TNB-specific evidence-based interventions for cardiovascular risk …
Cardiovascular disease is the leading cause of morbidity and mortality globally. Transgender and nonbinary (TNB) individuals face unc …
Loss of chromosome Y in regulatory T cells.
Mattisson J, Halvardson J, Davies H, Bruhn-Olszewska B, Olszewski P, Danielsson M, Bjurling J, Lindberg A, Zaghlool A, Rychlicka-Buniowska E, Dumanski JP, Forsberg LA. Mattisson J, et al. BMC Genomics. 2024 Mar 5;25(1):243. doi: 10.1186/s12864-024-10168-7. BMC Genomics. 2024. PMID: 38443832 Free PMC article.
BACKGROUND: Mosaic loss of chromosome Y (LOY) in leukocytes is the most prevalent somatic aneuploidy in aging humans. Men with LOY have increased risks of all-cause mortality and the major causes of death, including many forms of cancer. ...
BACKGROUND: Mosaic loss of chromosome Y (LOY) in leukocytes is the most prevalent somatic aneuploidy in aging humans. Men with LOY have incr …
Loss of Y in leukocytes as a risk factor for critical COVID-19 in men.
Bruhn-Olszewska B, Davies H, Sarkisyan D, Juhas U, Rychlicka-Buniowska E, Wójcik M, Horbacz M, Jąkalski M, Olszewski P, Westholm JO, Smialowska A, Wierzba K, Torinsson Naluai Å, Jern N, Andersson LM, Järhult JD, Filipowicz N, Tiensuu Janson E, Rubertsson S, Lipcsey M, Gisslén M, Hultström M, Frithiof R, Dumanski JP. Bruhn-Olszewska B, et al. Genome Med. 2022 Dec 14;14(1):139. doi: 10.1186/s13073-022-01144-5. Genome Med. 2022. PMID: 36514076 Free PMC article.
BACKGROUND: The COVID-19 pandemic, which has a prominent social and economic impact worldwide, shows a largely unexplained male bias for the severity and mortality of the disease. Loss of chromosome Y (LOY) is a risk factor candidate in COVID-19 due to its prior associatio …
BACKGROUND: The COVID-19 pandemic, which has a prominent social and economic impact worldwide, shows a largely unexplained male bias for the …
Sex, gender and COVID-19: a call to action.
Ahmed SB, Dumanski SM. Ahmed SB, et al. Can J Public Health. 2020 Dec;111(6):980-983. doi: 10.17269/s41997-020-00417-z. Epub 2020 Sep 29. Can J Public Health. 2020. PMID: 32990927 Free PMC article.
Despite similar global rates of infection with Severe Acute Respiratory Syndrome-Coronavirus-2 (SARS-CoV-2, the virus responsible for the COVID-19 pandemic), hospitalizations and mortality are higher in men than in women. Females may be less vulnerable to viral infection d …
Despite similar global rates of infection with Severe Acute Respiratory Syndrome-Coronavirus-2 (SARS-CoV-2, the virus responsible for the CO …
Anti-Müllerian hormone and vascular dysfunction in women with chronic kidney disease.
Dumanski SM, Anderson TJ, Nerenberg KA, Holroyd-Leduc J, MacRae J, Raj SR, Metcalfe A, Ramesh S, Kalenga CZ, Sola D, Pajevic M, Ahmed SB. Dumanski SM, et al. Physiol Rep. 2022 Jan;10(2):e15154. doi: 10.14814/phy2.15154. Physiol Rep. 2022. PMID: 35075809 Free PMC article.
Young women with chronic kidney disease (CKD) have disproportionately increased risk of cardiovascular mortality. Reduced anti-Mullerian hormone (AMH) is linked to poor cardiovascular outcomes in the general population, but whether AMH is associated with increased cardiova …
Young women with chronic kidney disease (CKD) have disproportionately increased risk of cardiovascular mortality. Reduced anti-Muller …
Leukocytes with chromosome Y loss have reduced abundance of the cell surface immunoprotein CD99.
Mattisson J, Danielsson M, Hammond M, Davies H, Gallant CJ, Nordlund J, Raine A, Edén M, Kilander L, Ingelsson M, Dumanski JP, Halvardson J, Forsberg LA. Mattisson J, et al. Sci Rep. 2021 Jul 26;11(1):15160. doi: 10.1038/s41598-021-94588-5. Sci Rep. 2021. PMID: 34312421 Free PMC article.
Mosaic loss of chromosome Y (LOY) in immune cells is a male-specific mutation associated with increased risk for morbidity and mortality. The CD99 gene, positioned in the pseudoautosomal regions of chromosomes X and Y, encodes a cell surface protein essential for several k …
Mosaic loss of chromosome Y (LOY) in immune cells is a male-specific mutation associated with increased risk for morbidity and mortality …
Gender-affirming estrogen therapy route of administration and cardiovascular risk: a systematic review and narrative synthesis.
Turino Miranda K, Kalenga CZ, Saad N, Dumanski SM, Collister D, Rytz CL, Lorenzetti DL, Chang DH, McClurg C, Sola DY, Ahmed SB. Turino Miranda K, et al. Am J Physiol Heart Circ Physiol. 2022 Nov 1;323(5):H861-H868. doi: 10.1152/ajpheart.00299.2022. Epub 2022 Sep 2. Am J Physiol Heart Circ Physiol. 2022. PMID: 36053748 Free article.
Randomized controlled trials and observational studies reporting cardiovascular outcomes, such as all-cause and cardiovascular mortality, adverse cardiovascular events, and cardiovascular risk factors in individuals using nonoral compared with oral gender-affirming estroge …
Randomized controlled trials and observational studies reporting cardiovascular outcomes, such as all-cause and cardiovascular mortality …
Immune cells lacking Y chromosome show dysregulation of autosomal gene expression.
Dumanski JP, Halvardson J, Davies H, Rychlicka-Buniowska E, Mattisson J, Moghadam BT, Nagy N, Węglarczyk K, Bukowska-Strakova K, Danielsson M, Olszewski P, Piotrowski A, Oerton E, Ambicka A, Przewoźnik M, Bełch Ł, Grodzicki T, Chłosta PL, Imreh S, Giedraitis V, Kilander L, Nordlund J, Ameur A, Gyllensten U, Johansson Å, Józkowicz A, Siedlar M, Klich-Rączka A, Jaszczyński J, Enroth S, Baran J, Ingelsson M, Perry JRB, Ryś J, Forsberg LA. Dumanski JP, et al. Cell Mol Life Sci. 2021 Apr;78(8):4019-4033. doi: 10.1007/s00018-021-03822-w. Epub 2021 Apr 10. Cell Mol Life Sci. 2021. PMID: 33837451 Free PMC article.
Epidemiological investigations show that mosaic loss of chromosome Y (LOY) in leukocytes is associated with earlier mortality and morbidity from many diseases in men. LOY is the most common acquired mutation and is associated with aberrant clonal expansion of cells, yet it …
Epidemiological investigations show that mosaic loss of chromosome Y (LOY) in leukocytes is associated with earlier mortality and mor …
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