Dyer RB - Search Results

1

Mutant huntingtin impairs axonal trafficking in mammalian neurons in vivo and in vitro.

Trushina E, Dyer RB, Badger JD 2nd, Ure D, Eide L, Tran DD, Vrieze BT, Legendre-Guillemin V, McPherson PS, Mandavilli BS, Van Houten B, Zeitlin S, McNiven M, Aebersold R, Hayden M, Parisi JE, Seeberg E, Dragatsis I, Doyle K, Bender A, Chacko C, McMurray CT. Trushina E, et al. Among authors: dyer rb. Mol Cell Biol. 2004 Sep;24(18):8195-209. doi: 10.1128/MCB.24.18.8195-8209.2004. Mol Cell Biol. 2004. PMID: 15340079 Free PMC article.

2

Mutant huntingtin inhibits clathrin-independent endocytosis and causes accumulation of cholesterol in vitro and in vivo.

Trushina E, Singh RD, Dyer RB, Cao S, Shah VH, Parton RG, Pagano RE, McMurray CT. Trushina E, et al. Among authors: dyer rb. Hum Mol Genet. 2006 Dec 15;15(24):3578-91. doi: 10.1093/hmg/ddl434. Hum Mol Genet. 2006. PMID: 17142251

3

Mutant protein in Huntington disease is resistant to proteolysis in affected brain.

Dyer RB, McMurray CT. Dyer RB, et al. Nat Genet. 2001 Nov;29(3):270-8. doi: 10.1038/ng745. Nat Genet. 2001. PMID: 11600884

4

Microtubule destabilization and nuclear entry are sequential steps leading to toxicity in Huntington's disease.

Trushina E, Heldebrant MP, Perez-Terzic CM, Bortolon R, Kovtun IV, Badger JD 2nd, Terzic A, Estévez A, Windebank AJ, Dyer RB, Yao J, McMurray CT. Trushina E, et al. Among authors: dyer rb. Proc Natl Acad Sci U S A. 2003 Oct 14;100(21):12171-6. doi: 10.1073/pnas.2034961100. Epub 2003 Oct 3. Proc Natl Acad Sci U S A. 2003. PMID: 14527999 Free PMC article.

5

GAA instability in Friedreich's Ataxia shares a common, DNA-directed and intraallelic mechanism with other trinucleotide diseases.

Gacy AM, Goellner GM, Spiro C, Chen X, Gupta G, Bradbury EM, Dyer RB, Mikesell MJ, Yao JZ, Johnson AJ, Richter A, Melançon SB, McMurray CT. Gacy AM, et al. Among authors: dyer rb. Mol Cell. 1998 Mar;1(4):583-93. doi: 10.1016/s1097-2765(00)80058-1. Mol Cell. 1998. PMID: 9660942 Free article.

6

FAVL elevation in human tumors disrupts Fanconi anemia pathway signaling and promotes genomic instability and tumor growth.

Zhang J, Zhao D, Park HK, Wang H, Dyer RB, Liu W, Klee GG, McNiven MA, Tindall DJ, Molina JR, Fei P. Zhang J, et al. Among authors: dyer rb. J Clin Invest. 2010 May;120(5):1524-34. doi: 10.1172/JCI40908. Epub 2010 Apr 19. J Clin Invest. 2010. PMID: 20407210 Free PMC article.

7

Role for SUR2A ED domain in allosteric coupling within the K(ATP) channel complex.

Karger AB, Park S, Reyes S, Bienengraeber M, Dyer RB, Terzic A, Alekseev AE. Karger AB, et al. Among authors: dyer rb. J Gen Physiol. 2008 Mar;131(3):185-96. doi: 10.1085/jgp.200709852. J Gen Physiol. 2008. PMID: 18299394 Free PMC article.

8

Protection conferred by myocardial ATP-sensitive K+ channels in pressure overload-induced congestive heart failure revealed in KCNJ11 Kir6.2-null mutant.

Yamada S, Kane GC, Behfar A, Liu XK, Dyer RB, Faustino RS, Miki T, Seino S, Terzic A. Yamada S, et al. Among authors: dyer rb. J Physiol. 2006 Dec 15;577(Pt 3):1053-65. doi: 10.1113/jphysiol.2006.119511. Epub 2006 Oct 12. J Physiol. 2006. PMID: 17038430 Free PMC article.

9

KCNJ11 gene knockout of the Kir6.2 KATP channel causes maladaptive remodeling and heart failure in hypertension.

Kane GC, Behfar A, Dyer RB, O'Cochlain DF, Liu XK, Hodgson DM, Reyes S, Miki T, Seino S, Terzic A. Kane GC, et al. Among authors: dyer rb. Hum Mol Genet. 2006 Aug 1;15(15):2285-97. doi: 10.1093/hmg/ddl154. Epub 2006 Jun 16. Hum Mol Genet. 2006. PMID: 16782803

10

Candidate serum biomarkers for prostate adenocarcinoma identified by mRNA differences in prostate tissue and verified with protein measurements in tissue and blood.

Klee EW, Bondar OP, Goodmanson MK, Dyer RB, Erdogan S, Bergstralh EJ, Bergen HR 3rd, Sebo TJ, Klee GG. Klee EW, et al. Among authors: dyer rb. Clin Chem. 2012 Mar;58(3):599-609. doi: 10.1373/clinchem.2011.171637. Epub 2012 Jan 12. Clin Chem. 2012. PMID: 22247499 Free PMC article.

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