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Pancreatic cancer exosomes initiate pre-metastatic niche formation in the liver.
Nat Cell Biol. 2015 Jun;17(6):816-26. doi: 10.1038/ncb3169. Epub 2015 May 18.
Nat Cell Biol. 2015.
PMID: 25985394
Free PMC article.
The nuclear transport receptor Importin-11 is a tumor suppressor that maintains PTEN protein.
Chen M, Nowak DG, Narula N, Robinson B, Watrud K, Ambrico A, Herzka TM, Zeeman ME, Minderer M, Zheng W, Ebbesen SH, Plafker KS, Stahlhut C, Wang VM, Wills L, Nasar A, Castillo-Martin M, Cordon-Cardo C, Wilkinson JE, Powers S, Sordella R, Altorki NK, Mittal V, Stiles BM, Plafker SM, Trotman LC.
Chen M, et al. Among authors: ebbesen sh.
J Cell Biol. 2017 Mar 6;216(3):641-656. doi: 10.1083/jcb.201604025. Epub 2017 Feb 13.
J Cell Biol. 2017.
PMID: 28193700
Free PMC article.
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Convergent loss of PTEN leads to clinical resistance to a PI(3)Kα inhibitor.
Juric D, Castel P, Griffith M, Griffith OL, Won HH, Ellis H, Ebbesen SH, Ainscough BJ, Ramu A, Iyer G, Shah RH, Huynh T, Mino-Kenudson M, Sgroi D, Isakoff S, Thabet A, Elamine L, Solit DB, Lowe SW, Quadt C, Peters M, Derti A, Schegel R, Huang A, Mardis ER, Berger MF, Baselga J, Scaltriti M.
Juric D, et al. Among authors: ebbesen sh.
Nature. 2015 Feb 12;518(7538):240-4. doi: 10.1038/nature13948. Epub 2014 Nov 17.
Nature. 2015.
PMID: 25409150
Free PMC article.
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Pten loss promotes MAPK pathway dependency in HER2/neu breast carcinomas.
Ebbesen SH, Scaltriti M, Bialucha CU, Morse N, Kastenhuber ER, Wen HY, Dow LE, Baselga J, Lowe SW.
Ebbesen SH, et al.
Proc Natl Acad Sci U S A. 2016 Mar 15;113(11):3030-5. doi: 10.1073/pnas.1523693113. Epub 2016 Feb 29.
Proc Natl Acad Sci U S A. 2016.
PMID: 26929372
Free PMC article.
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Conditional reverse tet-transactivator mouse strains for the efficient induction of TRE-regulated transgenes in mice.
Dow LE, Nasr Z, Saborowski M, Ebbesen SH, Manchado E, Tasdemir N, Lee T, Pelletier J, Lowe SW.
Dow LE, et al. Among authors: ebbesen sh.
PLoS One. 2014 Apr 17;9(4):e95236. doi: 10.1371/journal.pone.0095236. eCollection 2014.
PLoS One. 2014.
PMID: 24743474
Free PMC article.
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