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Refining the accuracy of validated target identification through coding variant fine-mapping in type 2 diabetes.
Mahajan A, Wessel J, Willems SM, Zhao W, Robertson NR, Chu AY, Gan W, Kitajima H, Taliun D, Rayner NW, Guo X, Lu Y, Li M, Jensen RA, Hu Y, Huo S, Lohman KK, Zhang W, Cook JP, Prins BP, Flannick J, Grarup N, Trubetskoy VV, Kravic J, Kim YJ, Rybin DV, Yaghootkar H, Müller-Nurasyid M, Meidtner K, Li-Gao R, Varga TV, Marten J, Li J, Smith AV, An P, Ligthart S, Gustafsson S, Malerba G, Demirkan A, Tajes JF, Steinthorsdottir V, Wuttke M, Lecoeur C, Preuss M, Bielak LF, Graff M, Highland HM, Justice AE, Liu DJ, Marouli E, Peloso GM, Warren HR; ExomeBP Consortium; MAGIC Consortium; GIANT Consortium; Afaq S, Afzal S, Ahlqvist E, Almgren P, Amin N, Bang LB, Bertoni AG, Bombieri C, Bork-Jensen J, Brandslund I, Brody JA, Burtt NP, Canouil M, Chen YI, Cho YS, Christensen C, Eastwood SV, Eckardt KU, Fischer K, Gambaro G, Giedraitis V, Grove ML, de Haan HG, Hackinger S, Hai Y, Han S, Tybjærg-Hansen A, Hivert MF, Isomaa B, Jäger S, Jørgensen ME, Jørgensen T, Käräjämäki A, Kim BJ, Kim SS, Koistinen HA, Kovacs P, Kriebel J, Kronenberg F, Läll K, Lange LA, Lee JJ, Lehne B, Li H, Lin KH, Linneberg A, Liu CT, Liu J, Loh M, Mägi R, Mamakou V, McKean-Cowdin R, Nadkarni G, Neville M, Nielsen SF, N… See abstract for full author list ➔ Mahajan A, et al. Among authors: eckardt ku. Nat Genet. 2018 Apr;50(4):559-571. doi: 10.1038/s41588-018-0084-1. Epub 2018 Apr 9. Nat Genet. 2018. PMID: 29632382 Free PMC article.
Prevalence and correlates of gout in a large cohort of patients with chronic kidney disease: the German Chronic Kidney Disease (GCKD) study.
Jing J, Kielstein JT, Schultheiss UT, Sitter T, Titze SI, Schaeffner ES, McAdams-DeMarco M, Kronenberg F, Eckardt KU, Köttgen A; GCKD Study Investigators. Jing J, et al. Among authors: eckardt ku. Nephrol Dial Transplant. 2015 Apr;30(4):613-21. doi: 10.1093/ndt/gfu352. Epub 2014 Nov 13. Nephrol Dial Transplant. 2015. PMID: 25395390
Heart failure in a cohort of patients with chronic kidney disease: the GCKD study.
Beck H, Titze SI, Hübner S, Busch M, Schlieper G, Schultheiss UT, Wanner C, Kronenberg F, Krane V, Eckardt KU, Köttgen A; GCKD Investigators. Beck H, et al. Among authors: eckardt ku. PLoS One. 2015 Apr 13;10(4):e0122552. doi: 10.1371/journal.pone.0122552. eCollection 2015. PLoS One. 2015. PMID: 25874373 Free PMC article.
Association of relative telomere length with cardiovascular disease in a large chronic kidney disease cohort: the GCKD study.
Raschenberger J, Kollerits B, Titze S, Köttgen A, Bärthlein B, Ekici AB, Forer L, Schönherr S, Weissensteiner H, Haun M, Wanner C, Eckardt KU, Kronenberg F; GCKD study Investigators. Raschenberger J, et al. Among authors: eckardt ku. Atherosclerosis. 2015 Oct;242(2):529-34. doi: 10.1016/j.atherosclerosis.2015.08.020. Epub 2015 Aug 14. Atherosclerosis. 2015. PMID: 26302167
Do telomeres have a higher plasticity than thought? Results from the German Chronic Kidney Disease (GCKD) study as a high-risk population.
Raschenberger J, Kollerits B, Titze S, Köttgen A, Bärthlein B, Ekici AB, Forer L, Schönherr S, Weissensteiner H, Haun M, Wanner C, Eckardt KU, Kronenberg F; GCKD study Investigators. Raschenberger J, et al. Among authors: eckardt ku. Exp Gerontol. 2015 Dec;72:162-6. doi: 10.1016/j.exger.2015.09.019. Epub 2015 Sep 28. Exp Gerontol. 2015. PMID: 26423240
Genetic risk variants for membranous nephropathy: extension of and association with other chronic kidney disease aetiologies.
Sekula P, Li Y, Stanescu HC, Wuttke M, Ekici AB, Bockenhauer D, Walz G, Powis SH, Kielstein JT, Brenchley P; GCKD Investigators; Eckardt KU, Kronenberg F, Kleta R, Köttgen A. Sekula P, et al. Among authors: eckardt ku. Nephrol Dial Transplant. 2017 Feb 1;32(2):325-332. doi: 10.1093/ndt/gfw001. Epub 2016 Feb 4. Nephrol Dial Transplant. 2017. PMID: 27333618 Free PMC article.
A novel but frequent variant in LPA KIV-2 is associated with a pronounced Lp(a) and cardiovascular risk reduction.
Coassin S, Erhart G, Weissensteiner H, Eca Guimarães de Araújo M, Lamina C, Schönherr S, Forer L, Haun M, Losso JL, Köttgen A, Schmidt K, Utermann G, Peters A, Gieger C, Strauch K, Finkenstedt A, Bale R, Zoller H, Paulweber B, Eckardt KU, Hüttenhofer A, Huber LA, Kronenberg F. Coassin S, et al. Among authors: eckardt ku. Eur Heart J. 2017 Jun 14;38(23):1823-1831. doi: 10.1093/eurheartj/ehx174. Eur Heart J. 2017. PMID: 28444229 Free PMC article.
659 results