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A novel pipeline of 2-(benzenesulfonamide)-N-(4-hydroxyphenyl) acetamide analgesics that lack hepatotoxicity and retain antipyresis.
Bazan HA, Bhattacharjee S, Burgos C, Recio J, Abet V, Pahng AR, Jun B, Heap J, Ledet AJ, Gordon WC, Edwards S, Paul D, Alvarez-Builla J, Bazan NG. Bazan HA, et al. Among authors: edwards s. Eur J Med Chem. 2020 Sep 15;202:112600. doi: 10.1016/j.ejmech.2020.112600. Epub 2020 Jun 30. Eur J Med Chem. 2020. PMID: 32629335 Free PMC article.
IL-10 normalizes aberrant amygdala GABA transmission and reverses anxiety-like behavior and dependence-induced escalation of alcohol intake.
Patel RR, Wolfe SA, Bajo M, Abeynaike S, Pahng A, Borgonetti V, D'Ambrosio S, Nikzad R, Edwards S, Paust S, Roberts AJ, Roberto M. Patel RR, et al. Among authors: edwards s. Prog Neurobiol. 2021 Apr;199:101952. doi: 10.1016/j.pneurobio.2020.101952. Epub 2020 Nov 13. Prog Neurobiol. 2021. PMID: 33197496 Free PMC article.
A vaccine strategy that induces protective immunity against heroin.
Stowe GN, Vendruscolo LF, Edwards S, Schlosburg JE, Misra KK, Schulteis G, Mayorov AV, Zakhari JS, Koob GF, Janda KD. Stowe GN, et al. Among authors: edwards s. J Med Chem. 2011 Jul 28;54(14):5195-204. doi: 10.1021/jm200461m. Epub 2011 Jun 30. J Med Chem. 2011. PMID: 21692508 Free PMC article.
3,634 results