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Properdin binding to complement activating surfaces depends on initial C3b deposition.
Proc Natl Acad Sci U S A. 2017 Jan 24;114(4):E534-E539. doi: 10.1073/pnas.1612385114. Epub 2017 Jan 9.
Proc Natl Acad Sci U S A. 2017.
PMID: 28069958
Free PMC article.
The alternative complement pathway is dysregulated in patients with chronic heart failure.
Shahini N, Michelsen AE, Nilsson PH, Ekholt K, Gullestad L, Broch K, Dahl CP, Aukrust P, Ueland T, Mollnes TE, Yndestad A, Louwe MC.
Shahini N, et al. Among authors: ekholt k.
Sci Rep. 2017 Feb 14;7:42532. doi: 10.1038/srep42532.
Sci Rep. 2017.
PMID: 28195242
Free PMC article.
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Platelet-Depletion of Whole Blood Reveals That Platelets Potentiate the Release of IL-8 From Leukocytes Into Plasma in a Thrombin-Dependent Manner.
Quach HQ, Johnson C, Ekholt K, Islam R, Mollnes TE, Nilsson PH.
Quach HQ, et al. Among authors: ekholt k.
Front Immunol. 2022 Apr 4;13:865386. doi: 10.3389/fimmu.2022.865386. eCollection 2022.
Front Immunol. 2022.
PMID: 35444648
Free PMC article.
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Thrombin Differentially Modulates the Acute Inflammatory Response to Escherichia coli and Staphylococcus aureus in Human Whole Blood.
Johnson C, Quach HQ, Lau C, Ekholt K, Espevik T, Woodruff TM, Pischke SE, Mollnes TE, Nilsson PH.
Johnson C, et al. Among authors: ekholt k.
J Immunol. 2022 Jun 15;208(12):2771-2778. doi: 10.4049/jimmunol.2101033. Epub 2022 Jun 8.
J Immunol. 2022.
PMID: 35675954
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IL-6 Receptor Inhibition by Tocilizumab Attenuated Expression of C5a Receptor 1 and 2 in Non-ST-Elevation Myocardial Infarction.
Orrem HL, Nilsson PH, Pischke SE, Kleveland O, Yndestad A, Ekholt K, Damås JK, Espevik T, Bendz B, Halvorsen B, Gregersen I, Wiseth R, Andersen GØ, Ueland T, Gullestad L, Aukrust P, Barratt-Due A, Mollnes TE.
Orrem HL, et al. Among authors: ekholt k.
Front Immunol. 2018 Sep 12;9:2035. doi: 10.3389/fimmu.2018.02035. eCollection 2018.
Front Immunol. 2018.
PMID: 30258440
Free PMC article.
Clinical Trial.
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