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A widely used sampling device in colorectal cancer screening programmes allows for large-scale microbiome studies.
Gudra D, Shoaie S, Fridmanis D, Klovins J, Wefer H, Silamikelis I, Peculis R, Kalnina I, Elbere I, Radovica-Spalvina I, Hultcrantz R, Šķenders Ģ, Leja M, Engstrand L. Gudra D, et al. Among authors: elbere i. Gut. 2019 Sep;68(9):1723-1725. doi: 10.1136/gutjnl-2018-316225. Epub 2018 Sep 21. Gut. 2019. PMID: 30242040 Free PMC article. No abstract available.
Significantly altered peripheral blood cell DNA methylation profile as a result of immediate effect of metformin use in healthy individuals.
Elbere I, Silamikelis I, Ustinova M, Kalnina I, Zaharenko L, Peculis R, Konrade I, Ciuculete DM, Zhukovsky C, Gudra D, Radovica-Spalvina I, Fridmanis D, Pirags V, Schiöth HB, Klovins J. Elbere I, et al. Clin Epigenetics. 2018 Dec 13;10(1):156. doi: 10.1186/s13148-018-0593-x. Clin Epigenetics. 2018. PMID: 30545422 Free PMC article. Clinical Trial.
Metformin strongly affects transcriptome of peripheral blood cells in healthy individuals.
Ustinova M, Silamikelis I, Kalnina I, Ansone L, Rovite V, Elbere I, Radovica-Spalvina I, Fridmanis D, Aladyeva J, Konrade I, Pirags V, Klovins J. Ustinova M, et al. Among authors: elbere i. PLoS One. 2019 Nov 8;14(11):e0224835. doi: 10.1371/journal.pone.0224835. eCollection 2019. PLoS One. 2019. PMID: 31703101 Free PMC article.
Epigenetic markers associated with metformin response and intolerance in drug-naïve patients with type 2 diabetes.
García-Calzón S, Perfilyev A, Martinell M, Ustinova M, Kalamajski S, Franks PW, Bacos K, Elbere I, Pihlajamäki J, Volkov P, Vaag A, Groop L, Maziarz M, Klovins J, Ahlqvist E, Ling C. García-Calzón S, et al. Among authors: elbere i. Sci Transl Med. 2020 Sep 16;12(561):eaaz1803. doi: 10.1126/scitranslmed.aaz1803. Sci Transl Med. 2020. PMID: 32938793
17 results