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Pan-cancer study detects genetic risk variants and shared genetic basis in two large cohorts.
Rashkin SR, Graff RE, Kachuri L, Thai KK, Alexeeff SE, Blatchins MA, Cavazos TB, Corley DA, Emami NC, Hoffman JD, Jorgenson E, Kushi LH, Meyers TJ, Van Den Eeden SK, Ziv E, Habel LA, Hoffmann TJ, Sakoda LC, Witte JS. Rashkin SR, et al. Among authors: emami nc. Nat Commun. 2020 Sep 4;11(1):4423. doi: 10.1038/s41467-020-18246-6. Nat Commun. 2020. PMID: 32887889 Free PMC article.
A large multiethnic genome-wide association study of prostate cancer identifies novel risk variants and substantial ethnic differences.
Hoffmann TJ, Van Den Eeden SK, Sakoda LC, Jorgenson E, Habel LA, Graff RE, Passarelli MN, Cario CL, Emami NC, Chao CR, Ghai NR, Shan J, Ranatunga DK, Quesenberry CP, Aaronson D, Presti J, Wang Z, Berndt SI, Chanock SJ, McDonnell SK, French AJ, Schaid DJ, Thibodeau SN, Li Q, Freedman ML, Penney KL, Mucci LA, Haiman CA, Henderson BE, Seminara D, Kvale MN, Kwok PY, Schaefer C, Risch N, Witte JS. Hoffmann TJ, et al. Among authors: emami nc. Cancer Discov. 2015 Aug;5(8):878-91. doi: 10.1158/2159-8290.CD-15-0315. Epub 2015 Jun 1. Cancer Discov. 2015. PMID: 26034056 Free PMC article.
Genome-wide association study of prostate-specific antigen levels identifies novel loci independent of prostate cancer.
Hoffmann TJ, Passarelli MN, Graff RE, Emami NC, Sakoda LC, Jorgenson E, Habel LA, Shan J, Ranatunga DK, Quesenberry CP, Chao CR, Ghai NR, Aaronson D, Presti J, Nordström T, Wang Z, Berndt SI, Chanock SJ, Mosley JD, Klein RJ, Middha M, Lilja H, Melander O, Kvale MN, Kwok PY, Schaefer C, Risch N, Van Den Eeden SK, Witte JS. Hoffmann TJ, et al. Among authors: emami nc. Nat Commun. 2017 Jan 31;8:14248. doi: 10.1038/ncomms14248. Nat Commun. 2017. PMID: 28139693 Free PMC article.
A Large-Scale Association Study Detects Novel Rare Variants, Risk Genes, Functional Elements, and Polygenic Architecture of Prostate Cancer Susceptibility.
Emami NC, Cavazos TB, Rashkin SR, Cario CL, Graff RE, Tai CG, Mefford JA, Kachuri L, Wan E, Wong S, Aaronson D, Presti J, Habel LA, Shan J, Ranatunga DK, Chao CR, Ghai NR, Jorgenson E, Sakoda LC, Kvale MN, Kwok PY, Schaefer C, Risch N, Hoffmann TJ, Van Den Eeden SK, Witte JS. Emami NC, et al. Cancer Res. 2021 Apr 1;81(7):1695-1703. doi: 10.1158/0008-5472.CAN-20-2635. Epub 2020 Dec 8. Cancer Res. 2021. PMID: 33293427 Free PMC article.
Immune-mediated genetic pathways resulting in pulmonary function impairment increase lung cancer susceptibility.
Kachuri L, Johansson M, Rashkin SR, Graff RE, Bossé Y, Manem V, Caporaso NE, Landi MT, Christiani DC, Vineis P, Liu G, Scelo G, Zaridze D, Shete SS, Albanes D, Aldrich MC, Tardón A, Rennert G, Chen C, Goodman GE, Doherty JA, Bickeböller H, Field JK, Davies MP, Dawn Teare M, Kiemeney LA, Bojesen SE, Haugen A, Zienolddiny S, Lam S, Le Marchand L, Cheng I, Schabath MB, Duell EJ, Andrew AS, Manjer J, Lazarus P, Arnold S, McKay JD, Emami NC, Warkentin MT, Brhane Y, Obeidat M, Martin RM, Relton C, Davey Smith G, Haycock PC, Amos CI, Brennan P, Witte JS, Hung RJ. Kachuri L, et al. Among authors: emami nc. Nat Commun. 2020 Jan 7;11(1):27. doi: 10.1038/s41467-019-13855-2. Nat Commun. 2020. PMID: 31911640 Free PMC article.
Cross-cancer evaluation of polygenic risk scores for 16 cancer types in two large cohorts.
Graff RE, Cavazos TB, Thai KK, Kachuri L, Rashkin SR, Hoffman JD, Alexeeff SE, Blatchins M, Meyers TJ, Leong L, Tai CG, Emami NC, Corley DA, Kushi LH, Ziv E, Van Den Eeden SK, Jorgenson E, Hoffmann TJ, Habel LA, Witte JS, Sakoda LC. Graff RE, et al. Among authors: emami nc. Nat Commun. 2021 Feb 12;12(1):970. doi: 10.1038/s41467-021-21288-z. Nat Commun. 2021. PMID: 33579919 Free PMC article.
Identification of Novel Susceptibility Loci and Genes for Prostate Cancer Risk: A Transcriptome-Wide Association Study in Over 140,000 European Descendants.
Wu L, Wang J, Cai Q, Cavazos TB, Emami NC, Long J, Shu XO, Lu Y, Guo X, Bauer JA, Pasaniuc B, Penney KL, Freedman ML, Kote-Jarai Z, Witte JS, Haiman CA, Eeles RA, Zheng W; PRACTICAL, CRUK, BPC3, CAPS, PEGASUS Consortia. Wu L, et al. Among authors: emami nc. Cancer Res. 2019 Jul 1;79(13):3192-3204. doi: 10.1158/0008-5472.CAN-18-3536. Epub 2019 May 17. Cancer Res. 2019. PMID: 31101764 Free PMC article.
13 results