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The extracellular matrix proteoglycan fibromodulin is upregulated in clinical and experimental heart failure and affects cardiac remodeling.
Andenæs K, Lunde IG, Mohammadzadeh N, Dahl CP, Aronsen JM, Strand ME, Palmero S, Sjaastad I, Christensen G, Engebretsen KVT, Tønnessen T. Andenæs K, et al. Among authors: engebretsen kvt. PLoS One. 2018 Jul 27;13(7):e0201422. doi: 10.1371/journal.pone.0201422. eCollection 2018. PLoS One. 2018. PMID: 30052659 Free PMC article.
The extracellular matrix proteoglycan lumican improves survival and counteracts cardiac dilatation and failure in mice subjected to pressure overload.
Mohammadzadeh N, Lunde IG, Andenæs K, Strand ME, Aronsen JM, Skrbic B, Marstein HS, Bandlien C, Nygård S, Gorham J, Sjaastad I, Chakravarti S, Christensen G, Engebretsen KVT, Tønnessen T. Mohammadzadeh N, et al. Among authors: engebretsen kvt. Sci Rep. 2019 Jun 24;9(1):9206. doi: 10.1038/s41598-019-45651-9. Sci Rep. 2019. PMID: 31235849 Free PMC article.
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