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LIMT is a novel metastasis inhibiting lncRNA suppressed by EGF and downregulated in aggressive breast cancer.
Sas-Chen A, Aure MR, Leibovich L, Carvalho S, Enuka Y, Körner C, Polycarpou-Schwarz M, Lavi S, Nevo N, Kuznetsov Y, Yuan J, Azuaje F; Oslo Breast Cancer Research Consortium (OSBREAC)SauerTorillGeislerJürgenHofvindSolveigBathenTone FBorgenElinEngebråtenOlavFodstadØysteinGarredØysteinGeitvikGry AarumKåresenRolfNaumeBjørnMælandsmoGunhild MariRussnesHege GSchlichtingEllenSørlieThereseLingjærdeOle ChristianSahlbergKristine KleiviSkjervenHelle KristineFritzmanBritt; Ulitsky I, Diederichs S, Wiemann S, Yakhini Z, Kristensen VN, Børresen-Dale AL, Yarden Y. Sas-Chen A, et al. Among authors: enuka y. EMBO Mol Med. 2016 Sep 1;8(9):1052-64. doi: 10.15252/emmm.201606198. Print 2016 Sep. EMBO Mol Med. 2016. PMID: 27485121 Free PMC article.
Diurnal suppression of EGFR signalling by glucocorticoids and implications for tumour progression and treatment.
Lauriola M, Enuka Y, Zeisel A, D'Uva G, Roth L, Sharon-Sevilla M, Lindzen M, Sharma K, Nevo N, Feldman M, Carvalho S, Cohen-Dvashi H, Kedmi M, Ben-Chetrit N, Chen A, Solmi R, Wiemann S, Schmitt F, Domany E, Yarden Y. Lauriola M, et al. Among authors: enuka y. Nat Commun. 2014 Oct 3;5:5073. doi: 10.1038/ncomms6073. Nat Commun. 2014. PMID: 25278152 Free PMC article.
Epigenetic mechanisms underlie the crosstalk between growth factors and a steroid hormone.
Enuka Y, Feldman ME, Chowdhury A, Srivastava S, Lindzen M, Sas-Chen A, Massart R, Cheishvili D, Suderman MJ, Zaltsman Y, Mazza CA, Shukla K, Körner C, Furth N, Lauriola M, Oren M, Wiemann S, Szyf M, Yarden Y. Enuka Y, et al. Nucleic Acids Res. 2017 Dec 15;45(22):12681-12699. doi: 10.1093/nar/gkx865. Nucleic Acids Res. 2017. PMID: 29036586 Free PMC article.
An oligoclonal antibody durably overcomes resistance of lung cancer to third-generation EGFR inhibitors.
Mancini M, Gal H, Gaborit N, Mazzeo L, Romaniello D, Salame TM, Lindzen M, Mahlknecht G, Enuka Y, Burton DG, Roth L, Noronha A, Marrocco I, Adreka D, Altstadter RE, Bousquet E, Downward J, Maraver A, Krizhanovsky V, Yarden Y. Mancini M, et al. Among authors: enuka y. EMBO Mol Med. 2018 Feb;10(2):294-308. doi: 10.15252/emmm.201708076. EMBO Mol Med. 2018. PMID: 29212784 Free PMC article.
SILAC identifies LAD1 as a filamin-binding regulator of actin dynamics in response to EGF and a marker of aggressive breast tumors.
Roth L, Srivastava S, Lindzen M, Sas-Chen A, Sheffer M, Lauriola M, Enuka Y, Noronha A, Mancini M, Lavi S, Tarcic G, Pines G, Nevo N, Heyman O, Ziv T, Rueda OM, Gnocchi D, Pikarsky E, Admon A, Caldas C, Yarden Y. Roth L, et al. Among authors: enuka y. Sci Signal. 2018 Jan 30;11(515):eaan0949. doi: 10.1126/scisignal.aan0949. Sci Signal. 2018. PMID: 29382783