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492 results

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HOTAIR and its surrogate DNA methylation signature indicate carboplatin resistance in ovarian cancer.
Teschendorff AE, Lee SH, Jones A, Fiegl H, Kalwa M, Wagner W, Chindera K, Evans I, Dubeau L, Orjalo A, Horlings HM, Niederreiter L, Kaser A, Yang W, Goode EL, Fridley BL, Jenner RG, Berns EM, Wik E, Salvesen HB, Wisman GB, van der Zee AG, Davidson B, Trope CG, Lambrechts S, Vergote I, Calvert H, Jacobs IJ, Widschwendter M. Teschendorff AE, et al. Among authors: evans i. Genome Med. 2015 Oct 24;7:108. doi: 10.1186/s13073-015-0233-4. Genome Med. 2015. PMID: 26497652 Free PMC article.
DNA methylation markers for early detection of women's cancer: promise and challenges.
Wittenberger T, Sleigh S, Reisel D, Zikan M, Wahl B, Alunni-Fabbroni M, Jones A, Evans I, Koch J, Paprotka T, Lempiäinen H, Rujan T, Rack B, Cibula D, Widschwendter M. Wittenberger T, et al. Among authors: evans i. Epigenomics. 2014 Jun;6(3):311-27. doi: 10.2217/epi.14.20. Epigenomics. 2014. PMID: 25111485 Free article. Review.
Methylation patterns in serum DNA for early identification of disseminated breast cancer.
Widschwendter M, Evans I, Jones A, Ghazali S, Reisel D, Ryan A, Gentry-Maharaj A, Zikan M, Cibula D, Eichner J, Alunni-Fabbroni M, Koch J, Janni WJ, Paprotka T, Wittenberger T, Menon U, Wahl B, Rack B, Lempiäinen H. Widschwendter M, et al. Among authors: evans i. Genome Med. 2017 Dec 22;9(1):115. doi: 10.1186/s13073-017-0499-9. Genome Med. 2017. PMID: 29268762 Free PMC article. Clinical Trial.
The potential of circulating tumor DNA methylation analysis for the early detection and management of ovarian cancer.
Widschwendter M, Zikan M, Wahl B, Lempiäinen H, Paprotka T, Evans I, Jones A, Ghazali S, Reisel D, Eichner J, Rujan T, Yang Z, Teschendorff AE, Ryan A, Cibula D, Menon U, Wittenberger T. Widschwendter M, et al. Among authors: evans i. Genome Med. 2017 Dec 22;9(1):116. doi: 10.1186/s13073-017-0500-7. Genome Med. 2017. PMID: 29268796 Free PMC article.
Epigenome-based cancer risk prediction: rationale, opportunities and challenges.
Widschwendter M, Jones A, Evans I, Reisel D, Dillner J, Sundström K, Steyerberg EW, Vergouwe Y, Wegwarth O, Rebitschek FG, Siebert U, Sroczynski G, de Beaufort ID, Bolt I, Cibula D, Zikan M, Bjørge L, Colombo N, Harbeck N, Dudbridge F, Tasse AM, Knoppers BM, Joly Y, Teschendorff AE, Pashayan N; FORECEE (4C) Consortium. Widschwendter M, et al. Among authors: evans i. Nat Rev Clin Oncol. 2018 May;15(5):292-309. doi: 10.1038/nrclinonc.2018.30. Epub 2018 Feb 27. Nat Rev Clin Oncol. 2018. PMID: 29485132 Review.
Association between the cervicovaginal microbiome, BRCA1 mutation status, and risk of ovarian cancer: a case-control study.
Nené NR, Reisel D, Leimbach A, Franchi D, Jones A, Evans I, Knapp S, Ryan A, Ghazali S, Timms JF, Paprotka T, Bjørge L, Zikan M, Cibula D, Colombo N, Widschwendter M. Nené NR, et al. Among authors: evans i. Lancet Oncol. 2019 Aug;20(8):1171-1182. doi: 10.1016/S1470-2045(19)30340-7. Epub 2019 Jul 9. Lancet Oncol. 2019. PMID: 31300207
DNA methylation signatures to predict the cervicovaginal microbiome status.
Nené NR, Barrett J, Jones A, Evans I, Reisel D, Timms JF, Paprotka T, Leimbach A, Franchi D, Colombo N, Bjørge L, Zikan M, Cibula D, Widschwendter M. Nené NR, et al. Among authors: evans i. Clin Epigenetics. 2020 Nov 23;12(1):180. doi: 10.1186/s13148-020-00966-7. Clin Epigenetics. 2020. PMID: 33228781 Free PMC article.
The WID-BC-index identifies women with primary poor prognostic breast cancer based on DNA methylation in cervical samples.
Barrett JE, Herzog C, Jones A, Leavy OC, Evans I, Knapp S, Reisel D, Nazarenko T, Kim YN, Franchi D, Ryan A, Franks J, Bjørge L, Zikan M, Cibula D, Harbeck N, Colombo N, Dudbridge F, Jones L, Sundström K, Dillner J, Rådestad AF, Gemzell-Danielsson K, Pashayan N, Widschwendter M. Barrett JE, et al. Among authors: evans i. Nat Commun. 2022 Feb 1;13(1):449. doi: 10.1038/s41467-021-27918-w. Nat Commun. 2022. PMID: 35105882 Free PMC article.
The DNA methylome of cervical cells can predict the presence of ovarian cancer.
Barrett JE, Jones A, Evans I, Reisel D, Herzog C, Chindera K, Kristiansen M, Leavy OC, Manchanda R, Bjørge L, Zikan M, Cibula D, Widschwendter M. Barrett JE, et al. Among authors: evans i. Nat Commun. 2022 Feb 1;13(1):448. doi: 10.1038/s41467-021-26615-y. Nat Commun. 2022. PMID: 35105887 Free PMC article.
Susceptibility to hormone-mediated cancer is reflected by different tick rates of the epithelial and general epigenetic clock.
Barrett JE, Herzog C, Kim YN, Bartlett TE, Jones A, Evans I, Cibula D, Zikan M, Bjørge L, Harbeck N, Colombo N, Howell SJ, Rådestad AF, Gemzell-Danielsson K, Widschwendter M. Barrett JE, et al. Among authors: evans i. Genome Biol. 2022 Feb 22;23(1):52. doi: 10.1186/s13059-022-02603-3. Genome Biol. 2022. PMID: 35189945 Free PMC article.
492 results