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The biliary epithelium presents antigens to and activates natural killer T cells.
Schrumpf E, Tan C, Karlsen TH, Sponheim J, Björkström NK, Sundnes O, Alfsnes K, Kaser A, Jefferson DM, Ueno Y, Eide TJ, Haraldsen G, Zeissig S, Exley MA, Blumberg RS, Melum E. Schrumpf E, et al. Among authors: exley ma. Hepatology. 2015 Oct;62(4):1249-59. doi: 10.1002/hep.27840. Epub 2015 May 20. Hepatology. 2015. PMID: 25855031 Free PMC article.
CD1d function is regulated by microsomal triglyceride transfer protein.
Brozovic S, Nagaishi T, Yoshida M, Betz S, Salas A, Chen D, Kaser A, Glickman J, Kuo T, Little A, Morrison J, Corazza N, Kim JY, Colgan SP, Young SG, Exley M, Blumberg RS. Brozovic S, et al. Nat Med. 2004 May;10(5):535-9. doi: 10.1038/nm1043. Epub 2004 Apr 25. Nat Med. 2004. PMID: 15107843
Primary deficiency of microsomal triglyceride transfer protein in human abetalipoproteinemia is associated with loss of CD1 function.
Zeissig S, Dougan SK, Barral DC, Junker Y, Chen Z, Kaser A, Ho M, Mandel H, McIntyre A, Kennedy SM, Painter GF, Veerapen N, Besra GS, Cerundolo V, Yue S, Beladi S, Behar SM, Chen X, Gumperz JE, Breckpot K, Raper A, Baer A, Exley MA, Hegele RA, Cuchel M, Rader DJ, Davidson NO, Blumberg RS. Zeissig S, et al. Among authors: exley ma. J Clin Invest. 2010 Aug;120(8):2889-99. doi: 10.1172/JCI42703. Epub 2010 Jul 1. J Clin Invest. 2010. PMID: 20592474 Free PMC article.
Control of CD1d-restricted antigen presentation and inflammation by sphingomyelin.
Melum E, Jiang X, Baker KD, Macedo MF, Fritsch J, Dowds CM, Wang J, Pharo A, Kaser A, Tan C, Pereira CS, Kelly SL, Duan J, Karlsen TH, Exley MA, Schütze S, Zajonc DM, Merrill AH, Schuchman EH, Zeissig S, Blumberg RS. Melum E, et al. Among authors: exley ma. Nat Immunol. 2019 Dec;20(12):1644-1655. doi: 10.1038/s41590-019-0504-0. Epub 2019 Oct 21. Nat Immunol. 2019. PMID: 31636468 Free PMC article.
A nano-engager for iNKT cells in cancer.
Exley MA, Gensollen T, Blumberg RS. Exley MA, et al. Nat Cancer. 2020 Nov;1(11):1032-1034. doi: 10.1038/s43018-020-00138-9. Nat Cancer. 2020. PMID: 35122067 No abstract available.
122 results