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Multiple-ancestry genome-wide association study identifies 27 loci associated with measures of hemolysis following blood storage.
Page GP, Kanias T, Guo YJ, Lanteri MC, Zhang X, Mast AE, Cable RG, Spencer BR, Kiss JE, Fang F, Endres-Dighe SM, Brambilla D, Nouraie M, Gordeuk VR, Kleinman S, Busch MP, Gladwin MT; National Heart, Lung, and Blood Institute (NHLBI) Recipient Epidemiology Donor Evaluation Study–III (REDS-III) program. Page GP, et al. Among authors: fang f. J Clin Invest. 2021 Jul 1;131(13):e146077. doi: 10.1172/JCI146077. J Clin Invest. 2021. PMID: 34014839 Free PMC article.
De novo mutations across 1,465 diverse genomes reveal mutational insights and reductions in the Amish founder population.
Kessler MD, Loesch DP, Perry JA, Heard-Costa NL, Taliun D, Cade BE, Wang H, Daya M, Ziniti J, Datta S, Celedón JC, Soto-Quiros ME, Avila L, Weiss ST, Barnes K, Redline SS, Vasan RS, Johnson AD, Mathias RA, Hernandez R, Wilson JG, Nickerson DA, Abecasis G, Browning SR, Zöllner S, O'Connell JR, Mitchell BD; National Heart, Lung, and Blood Institute Trans-Omics for Precision Medicine (TOPMed) Consortium; TOPMed Population Genetics Working Group; O'Connor TD. Kessler MD, et al. Proc Natl Acad Sci U S A. 2020 Feb 4;117(5):2560-2569. doi: 10.1073/pnas.1902766117. Epub 2020 Jan 21. Proc Natl Acad Sci U S A. 2020. PMID: 31964835 Free PMC article.
Blood donor obesity is associated with changes in red blood cell metabolism and susceptibility to hemolysis in cold storage and in response to osmotic and oxidative stress.
Hazegh K, Fang F, Bravo MD, Tran JQ, Muench MO, Jackman RP, Roubinian N, Bertolone L, DʼAlessandro A, Dumont L, Page GP, Kanias T. Hazegh K, et al. Among authors: fang f. Transfusion. 2021 Feb;61(2):435-448. doi: 10.1111/trf.16168. Epub 2020 Nov 4. Transfusion. 2021. PMID: 33146433 Free PMC article.
Donor genetic and nongenetic factors affecting red blood cell transfusion effectiveness.
Roubinian NH, Reese SE, Qiao H, Plimier C, Fang F, Page GP, Cable RG, Custer B, Gladwin MT, Goel R, Harris B, Hendrickson JE, Kanias T, Kleinman S, Mast AE, Sloan SR, Spencer BR, Spitalnik SL, Busch MP, Hod EA; National Heart Lung and Blood Institute (NHLBI) Recipient Epidemiology and Donor Evaluation Study IV Pediatrics (REDS-IV-P). Roubinian NH, et al. Among authors: fang f. JCI Insight. 2022 Jan 11;7(1):e152598. doi: 10.1172/jci.insight.152598. JCI Insight. 2022. PMID: 34793330 Free PMC article.
GAWMerge expands GWAS sample size and diversity by combining array-based genotyping and whole-genome sequencing.
Mathur R, Fang F, Gaddis N, Hancock DB, Cho MH, Hokanson JE, Bierut LJ, Lutz SM, Young K, Smith AV; NHLBI Trans-Omics for Precision Medicine (TOPMed) Consortium; Silverman EK, Page GP, Johnson EO. Mathur R, et al. Among authors: fang f. Commun Biol. 2022 Aug 11;5(1):806. doi: 10.1038/s42003-022-03738-6. Commun Biol. 2022. PMID: 35953715 Free PMC article.
Genome-wide association study of early ischaemic stroke risk in Brazilian individuals with sickle cell disease implicates ADAMTS2 and CDK18 and uncovers novel loci.
Earley EJ, Kelly S, Fang F, Alencar CS, Rodrigues DOW, Soares Cruz DT, Flanagan JM, Ware RE, Zhang X, Gordeuk V, Gladwin M, Zhang Y, Nouraie M, Nekhai S, Sabino E, Custer B, Dinardo C, Page GP; International Component of the NHLBI Recipient Epidemiology and Donor Evaluation Study (REDS-III) and the NHLBI Trans-Omics for Precision Medicine (TOPMed) Consortium. Earley EJ, et al. Among authors: fang f. Br J Haematol. 2023 Apr;201(2):343-352. doi: 10.1111/bjh.18637. Epub 2023 Jan 5. Br J Haematol. 2023. PMID: 36602125 Free PMC article.
4,576 results