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Genetic variation at the locus encompassing 11-beta hydroxylase and aldosterone synthase accounts for heritability in cortisol precursor (11-deoxycortisol) urinary metabolite excretion.
Keavney B, Mayosi B, Gaukrodger N, Imrie H, Baker M, Fraser R, Ingram M, Watkins H, Farrall M, Davies E, Connell J. Keavney B, et al. Among authors: farrall m. J Clin Endocrinol Metab. 2005 Feb;90(2):1072-7. doi: 10.1210/jc.2004-0870. Epub 2004 Nov 2. J Clin Endocrinol Metab. 2005. PMID: 15522937
Two-dimensional genome-scan identifies novel epistatic loci for essential hypertension.
Bell JT, Wallace C, Dobson R, Wiltshire S, Mein C, Pembroke J, Brown M, Clayton D, Samani N, Dominiczak A, Webster J, Lathrop GM, Connell J, Munroe P, Caulfield M, Farrall M. Bell JT, et al. Among authors: farrall m. Hum Mol Genet. 2006 Apr 15;15(8):1365-74. doi: 10.1093/hmg/ddl058. Epub 2006 Mar 16. Hum Mol Genet. 2006. PMID: 16543358
Genome-wide mapping of susceptibility to coronary artery disease identifies a novel replicated locus on chromosome 17.
Farrall M, Green FR, Peden JF, Olsson PG, Clarke R, Hellenius ML, Rust S, Lagercrantz J, Franzosi MG, Schulte H, Carey A, Olsson G, Assmann G, Tognoni G, Collins R, Hamsten A, Watkins H. Farrall M, et al. PLoS Genet. 2006 May;2(5):e72. doi: 10.1371/journal.pgen.0020072. Epub 2006 May 19. PLoS Genet. 2006. PMID: 16710446 Free PMC article.
324 results