Fearon K - Search Results

1

Gene expression analysis by massively parallel signature sequencing (MPSS) on microbead arrays.

Brenner S, Johnson M, Bridgham J, Golda G, Lloyd DH, Johnson D, Luo S, McCurdy S, Foy M, Ewan M, Roth R, George D, Eletr S, Albrecht G, Vermaas E, Williams SR, Moon K, Burcham T, Pallas M, DuBridge RB, Kirchner J, Fearon K, Mao J, Corcoran K. Brenner S, et al. Among authors: fearon k. Nat Biotechnol. 2000 Jun;18(6):630-4. doi: 10.1038/76469. Nat Biotechnol. 2000. PMID: 10835600

2

N3'-->P5' Oligodeoxyribonucleotide Phosphoramidates: A New Method of Synthesis Based on a Phosphoramidite Amine-Exchange Reaction.

Nelson JS, Fearon KL, Nguyen MQ, McCurdy SN, Frediani JE, Foy MF, Hirschbein BL. Nelson JS, et al. J Org Chem. 1997 Oct 17;62(21):7278-7287. doi: 10.1021/jo970801t. J Org Chem. 1997. PMID: 11671841

3

An improved synthesis of oligodeoxynucleotide N3'-->P5' phosphoramidates and their chimera using hindered phosphoramidite monomers and a novel handle for reverse phase purification.

Fearon KL, Hirschbein BL, Nelson JS, Foy MF, Nguyen MQ, Okruszek A, McCurdy SN, Frediani JE, DeDionisio LA, Raible AM, Cagle EN, Boyd V. Fearon KL, et al. Nucleic Acids Res. 1998 Aug 15;26(16):3813-24. doi: 10.1093/nar/26.16.3813. Nucleic Acids Res. 1998. PMID: 9685501 Free PMC article.

4

The manufacture and molecular characterization of phosphorothioate deoxynucleotides for use as antisense therapeutics in human clinical trials.

Bergot BJ, Foy M, Hansen C, Fearon K, Frediani J, Hirschbein B. Bergot BJ, et al. Among authors: fearon k. Nucleic Acids Symp Ser. 1993;(29):57. Nucleic Acids Symp Ser. 1993. PMID: 8247794 No abstract available.

5

31P NMR spectroscopy in oligonucleotide research and development.

Hirschbein BL, Fearon KL. Hirschbein BL, et al. Among authors: fearon kl. Antisense Nucleic Acid Drug Dev. 1997 Feb;7(1):55-61. doi: 10.1089/oli.1.1997.7.55. Antisense Nucleic Acid Drug Dev. 1997. PMID: 9055040 Review.

6

Synthesis and purification of oligonucleotide N3'-->P5' phosphoramidates and their phosphodiester and phosphorothioate chimeras.

Fearon KL, Nelson JS. Fearon KL, et al. Curr Protoc Nucleic Acid Chem. 2001 May;Chapter 4:Unit 4.7. doi: 10.1002/0471142700.nc0407s03. Curr Protoc Nucleic Acid Chem. 2001. PMID: 18428854

7

Comparison of binding of N3'-->P5' phosphoramidate and phosphorothioate oligonucleotides to cell surface proteins of cultured cells.

Hawley P, Nelson JS, Fearon KL, Zon G, Gibson I. Hawley P, et al. Among authors: fearon kl. Antisense Nucleic Acid Drug Dev. 1999 Feb;9(1):61-9. doi: 10.1089/oli.1.1999.9.61. Antisense Nucleic Acid Drug Dev. 1999. PMID: 10192290

8

Phosphorothioate oligodeoxynucleotides: large-scale synthesis and analysis, impurity characterization, and the effects of phosphorus stereochemistry.

Fearon KL, Hirschbein BL, Chiu CY, Quijano MR, Zon G. Fearon KL, et al. Ciba Found Symp. 1997;209:19-31; discussion 31-7. doi: 10.1002/9780470515396.ch3. Ciba Found Symp. 1997. PMID: 9383566 Review.

9

Investigation of the 'n-1' impurity in phosphorothioate oligodeoxynucleotides synthesized by the solid-phase beta-cyanoethyl phosphoramidite method using stepwise sulfurization.

Fearon KL, Stults JT, Bergot BJ, Christensen LM, Raible AM. Fearon KL, et al. Nucleic Acids Res. 1995 Jul 25;23(14):2754-61. doi: 10.1093/nar/23.14.2754. Nucleic Acids Res. 1995. PMID: 7651837 Free PMC article.

10

Real time kinetics of restriction endonuclease cleavage monitored by fluorescence resonance energy transfer.

Ghosh SS, Eis PS, Blumeyer K, Fearon K, Millar DP. Ghosh SS, et al. Among authors: fearon k. Nucleic Acids Res. 1994 Aug 11;22(15):3155-9. doi: 10.1093/nar/22.15.3155. Nucleic Acids Res. 1994. PMID: 8065930 Free PMC article.

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