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TGF-β inhibitor therapy decreases fibrosis and stimulates cardiac improvement in a pre-clinical study of chronic Chagas' heart disease.
Ferreira RR, Abreu RDS, Vilar-Pereira G, Degrave W, Meuser-Batista M, Ferreira NVC, da Cruz Moreira O, da Silva Gomes NL, Mello de Souza E, Ramos IP, Bailly S, Feige JJ, Lannes-Vieira J, de Araújo-Jorge TC, Waghabi MC. Ferreira RR, et al. Among authors: feige jj. PLoS Negl Trop Dis. 2019 Jul 31;13(7):e0007602. doi: 10.1371/journal.pntd.0007602. eCollection 2019 Jul. PLoS Negl Trop Dis. 2019. PMID: 31365537 Free PMC article.
TGF-β Polymorphisms Are a Risk Factor for Chagas Disease.
Ferreira RR, Madeira FDS, Alves GF, Chambela MDC, Curvo EOV, Moreira ADS, Almeida de Sá R, Mendonça-Lima L, Cabello PH, Bailly S, Feige JJ, Araujo-Jorge TC, Saraiva RM, Waghabi MC. Ferreira RR, et al. Among authors: feige jj. Dis Markers. 2018 Feb 18;2018:4579198. doi: 10.1155/2018/4579198. eCollection 2018. Dis Markers. 2018. PMID: 29670670 Free PMC article.
Cruzipain Activates Latent TGF-β from Host Cells during T. cruzi Invasion.
Ferrão PM, d'Avila-Levy CM, Araujo-Jorge TC, Degrave WM, Gonçalves Ada S, Garzoni LR, Lima AP, Feige JJ, Bailly S, Mendonça-Lima L, Waghabi MC. Ferrão PM, et al. Among authors: feige jj. PLoS One. 2015 May 4;10(5):e0124832. doi: 10.1371/journal.pone.0124832. eCollection 2015. PLoS One. 2015. PMID: 25938232 Free PMC article.
SB-431542, a transforming growth factor beta inhibitor, impairs Trypanosoma cruzi infection in cardiomyocytes and parasite cycle completion.
Waghabi MC, Keramidas M, Calvet CM, Meuser M, de Nazaré C Soeiro M, Mendonça-Lima L, Araújo-Jorge TC, Feige JJ, Bailly S. Waghabi MC, et al. Among authors: feige jj. Antimicrob Agents Chemother. 2007 Aug;51(8):2905-10. doi: 10.1128/AAC.00022-07. Epub 2007 May 25. Antimicrob Agents Chemother. 2007. PMID: 17526757 Free PMC article.
193 results