Aminolevulinate synthase: lysine 313 is not essential for binding the pyridoxal phosphate cofactor but is essential for catalysis.
Ferreira GC, Vajapey U, Hafez O, Hunter GA, Barber MJ.
Ferreira GC, et al.
Protein Sci. 1995 May;4(5):1001-6. doi: 10.1002/pro.5560040520.
Protein Sci. 1995.
PMID: 7663334
Free PMC article.
Lysine-313 of the mouse erythroid aminolevulinate synthase was recently identified to be linked covalently to the pyridoxal 5'-phosphate cofactor (Ferreira GC, Neame PJ, Dailey HA, 1993, Protein Sci 2:1959-1965). Here we report on the effect of replacement of aminol …
Lysine-313 of the mouse erythroid aminolevulinate synthase was recently identified to be linked covalently to the pyridoxal 5'-phosphate cof …