Ferrer M - Search Results

1

Structural Insights into the Activation of Human Relaxin Family Peptide Receptor 1 by Small-Molecule Agonists.

Hu X, Myhr C, Huang Z, Xiao J, Barnaeva E, Ho BA, Agoulnik IU, Ferrer M, Marugan JJ, Southall N, Agoulnik AI. Hu X, et al. Among authors: ferrer m. Biochemistry. 2016 Mar 29;55(12):1772-83. doi: 10.1021/acs.biochem.5b01195. Epub 2016 Mar 4. Biochemistry. 2016. PMID: 26866459 Free PMC article.

2

Novel patient cell-based HTS assay for identification of small molecules for a lysosomal storage disease.

Geng H, Whiteley G, Ribbens J, Zheng W, Southall N, Hu X, Marugan JJ, Ferrer M, Maegawa GH. Geng H, et al. Among authors: ferrer m. PLoS One. 2011;6(12):e29504. doi: 10.1371/journal.pone.0029504. Epub 2011 Dec 21. PLoS One. 2011. PMID: 22216298 Free PMC article.

3

Identification of a selective small-molecule inhibitor series targeting the eyes absent 2 (Eya2) phosphatase activity.

Krueger AB, Dehdashti SJ, Southall N, Marugan JJ, Ferrer M, Li X, Ford HL, Zheng W, Zhao R. Krueger AB, et al. Among authors: ferrer m. J Biomol Screen. 2013 Jan;18(1):85-96. doi: 10.1177/1087057112453936. Epub 2012 Jul 20. J Biomol Screen. 2013. PMID: 22820394 Free PMC article.

4

Discovery of a novel noniminosugar acid α glucosidase chaperone series.

Xiao J, Westbroek W, Motabar O, Lea WA, Hu X, Velayati A, Zheng W, Southall N, Gustafson AM, Goldin E, Sidransky E, Liu K, Simeonov A, Tamargo RJ, Ribes A, Matalonga L, Ferrer M, Marugan JJ. Xiao J, et al. Among authors: ferrer m. J Med Chem. 2012 Sep 13;55(17):7546-59. doi: 10.1021/jm3005543. Epub 2012 Aug 17. J Med Chem. 2012. PMID: 22834902 Free PMC article.

5

A high-throughput screening assay using Krabbe disease patient cells.

Ribbens J, Whiteley G, Furuya H, Southall N, Hu X, Marugan J, Ferrer M, Maegawa GH. Ribbens J, et al. Among authors: ferrer m. Anal Biochem. 2013 Mar 1;434(1):15-25. doi: 10.1016/j.ab.2012.10.034. Epub 2012 Nov 5. Anal Biochem. 2013. PMID: 23138179 Free PMC article.

6

Identification of small-molecule agonists of human relaxin family receptor 1 (RXFP1) by using a homogenous cell-based cAMP assay.

Chen CZ, Southall N, Xiao J, Marugan JJ, Ferrer M, Hu X, Jones RE, Feng S, Agoulnik IU, Zheng W, Agoulnik AI. Chen CZ, et al. Among authors: ferrer m. J Biomol Screen. 2013 Jul;18(6):670-7. doi: 10.1177/1087057112469406. Epub 2012 Dec 4. J Biomol Screen. 2013. PMID: 23212924 Free PMC article.

7

Identification and optimization of small-molecule agonists of the human relaxin hormone receptor RXFP1.

Xiao J, Huang Z, Chen CZ, Agoulnik IU, Southall N, Hu X, Jones RE, Ferrer M, Zheng W, Agoulnik AI, Marugan JJ. Xiao J, et al. Among authors: ferrer m. Nat Commun. 2013;4:1953. doi: 10.1038/ncomms2953. Nat Commun. 2013. PMID: 23764525 Free PMC article.

8

Discovery, optimization, and characterization of novel D2 dopamine receptor selective antagonists.

Xiao J, Free RB, Barnaeva E, Conroy JL, Doyle T, Miller B, Bryant-Genevier M, Taylor MK, Hu X, Dulcey AE, Southall N, Ferrer M, Titus S, Zheng W, Sibley DR, Marugan JJ. Xiao J, et al. Among authors: ferrer m. J Med Chem. 2014 Apr 24;57(8):3450-63. doi: 10.1021/jm500126s. Epub 2014 Apr 10. J Med Chem. 2014. PMID: 24666157 Free PMC article.

9

A high throughput screening assay system for the identification of small molecule inhibitors of gsp.

Bhattacharyya N, Hu X, Chen CZ, Mathews Griner LA, Zheng W, Inglese J, Austin CP, Marugan JJ, Southall N, Neumann S, Northup JK, Ferrer M, Collins MT. Bhattacharyya N, et al. Among authors: ferrer m. PLoS One. 2014 Mar 25;9(3):e90766. doi: 10.1371/journal.pone.0090766. eCollection 2014. PLoS One. 2014. PMID: 24667240 Free PMC article.

10

Allosteric inhibitors of the Eya2 phosphatase are selective and inhibit Eya2-mediated cell migration.

Krueger AB, Drasin DJ, Lea WA, Patrick AN, Patnaik S, Backos DS, Matheson CJ, Hu X, Barnaeva E, Holliday MJ, Blevins MA, Robin TP, Eisenmesser EZ, Ferrer M, Simeonov A, Southall N, Reigan P, Marugan J, Ford HL, Zhao R. Krueger AB, et al. Among authors: ferrer m. J Biol Chem. 2014 Jun 6;289(23):16349-61. doi: 10.1074/jbc.M114.566729. Epub 2014 Apr 22. J Biol Chem. 2014. PMID: 24755226 Free PMC article.

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