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Functional multivesicular bodies are required for autophagic clearance of protein aggregates associated with neurodegenerative disease.
J Cell Biol. 2007 Nov 5;179(3):485-500. doi: 10.1083/jcb.200702115.
J Cell Biol. 2007.
PMID: 17984323
Free PMC article.
The selective macroautophagic degradation of aggregated proteins requires the PI3P-binding protein Alfy.
Filimonenko M, Isakson P, Finley KD, Anderson M, Jeong H, Melia TJ, Bartlett BJ, Myers KM, Birkeland HC, Lamark T, Krainc D, Brech A, Stenmark H, Simonsen A, Yamamoto A.
Filimonenko M, et al.
Mol Cell. 2010 Apr 23;38(2):265-79. doi: 10.1016/j.molcel.2010.04.007.
Mol Cell. 2010.
PMID: 20417604
Free PMC article.
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