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Discovery of Vibegron: A Potent and Selective β3 Adrenergic Receptor Agonist for the Treatment of Overactive Bladder.
Edmondson SD, Zhu C, Kar NF, Di Salvo J, Nagabukuro H, Sacre-Salem B, Dingley K, Berger R, Goble SD, Morriello G, Harper B, Moyes CR, Shen DM, Wang L, Ball R, Fitzmaurice A, Frenkl T, Gichuru LN, Ha S, Hurley AL, Jochnowitz N, Levorse D, Mistry S, Miller RR, Ormes J, Salituro GM, Sanfiz A, Stevenson AS, Villa K, Zamlynny B, Green S, Struthers M, Weber AE. Edmondson SD, et al. Among authors: fitzmaurice a. J Med Chem. 2016 Jan 28;59(2):609-23. doi: 10.1021/acs.jmedchem.5b01372. Epub 2016 Jan 8. J Med Chem. 2016. PMID: 26709102
Pharmacological Characterization of a Novel Beta 3 Adrenergic Agonist, Vibegron: Evaluation of Antimuscarinic Receptor Selectivity for Combination Therapy for Overactive Bladder.
Di Salvo J, Nagabukuro H, Wickham LA, Abbadie C, DeMartino JA, Fitzmaurice A, Gichuru L, Kulick A, Donnelly MJ, Jochnowitz N, Hurley AL, Pereira A, Sanfiz A, Veronin G, Villa K, Woods J, Zamlynny B, Zycband E, Salituro GM, Frenkl T, Weber AE, Edmondson SD, Struthers M. Di Salvo J, et al. Among authors: fitzmaurice a. J Pharmacol Exp Ther. 2017 Feb;360(2):346-355. doi: 10.1124/jpet.116.237313. Epub 2016 Dec 13. J Pharmacol Exp Ther. 2017. PMID: 27965369
Design, synthesis, and evaluation of conformationally restricted acetanilides as potent and selective β3 adrenergic receptor agonists for the treatment of overactive bladder.
Moyes CR, Berger R, Goble SD, Harper B, Shen DM, Wang L, Bansal A, Brown PN, Chen AS, Dingley KH, Di Salvo J, Fitzmaurice A, Gichuru LN, Hurley AL, Jochnowitz N, Miller RR, Mistry S, Nagabukuro H, Salituro GM, Sanfiz A, Stevenson AS, Villa K, Zamlynny B, Struthers M, Weber AE, Edmondson SD. Moyes CR, et al. Among authors: fitzmaurice a. J Med Chem. 2014 Feb 27;57(4):1437-53. doi: 10.1021/jm4017224. Epub 2014 Feb 5. J Med Chem. 2014. PMID: 24437735
Scale-Up of HIV Antiretroviral Therapy and Estimation of Averted Infections and HIV-Related Deaths - Uganda, 2004-2022.
Dirlikov E, Kamoga J, Talisuna SA, Namusobya J, Kasozi DE, Akao J, Birabwa E, Ward JA, Elur B, Shiraishi RW, Corcoran C, Vasireddy V, Nelson R, Nelson LJ, Borgman M, Magongo EN, Kisaakye LN, Katureebe C, Kirungi W, Musinguzi J; PEPFAR Uganda. Dirlikov E, et al. MMWR Morb Mortal Wkly Rep. 2023 Jan 27;72(4):90-94. doi: 10.15585/mmwr.mm7204a2. MMWR Morb Mortal Wkly Rep. 2023. PMID: 36701255 Free PMC article.
Notes from the Field: Outbreak of Ebola Virus Disease Caused by Sudan ebolavirus - Uganda, August-October 2022.
Kiggundu T, Ario AR, Kadobera D, Kwesiga B, Migisha R, Makumbi I, Eurien D, Kabami Z, Kayiwa J, Lubwama B, Okethwangu D, Nabadda S, Bwire G, Mulei S, Harris JR, Dirlikov E, Fitzmaurice AG, Nabatanzi S, Tegegn Y, Muruta AN, Kyabayinze D, Boore AL, Kagirita A, Kyobe-Bosa H, Mwebesa HG, Atwine D, Aceng Ocero JR; Uganda Ebola Response Team. Kiggundu T, et al. Among authors: fitzmaurice ag. MMWR Morb Mortal Wkly Rep. 2022 Nov 11;71(45):1457-1459. doi: 10.15585/mmwr.mm7145a5. MMWR Morb Mortal Wkly Rep. 2022. PMID: 36355610 Free PMC article. No abstract available.
Risk perception and psychological state of healthcare workers in referral hospitals during the early phase of the COVID-19 pandemic, Uganda.
Migisha R, Ario AR, Kwesiga B, Bulage L, Kadobera D, Kabwama SN, Katana E, Ndyabakira A, Wadunde I, Byaruhanga A, Amanya G, Harris JR, Fitzmaurice AG. Migisha R, et al. Among authors: fitzmaurice ag. BMC Psychol. 2021 Dec 17;9(1):195. doi: 10.1186/s40359-021-00706-3. BMC Psychol. 2021. PMID: 34920763 Free PMC article.
57 results