Francis B - Search Results

1

Antiobesity efficacy of a novel cannabinoid-1 receptor inverse agonist, N-[(1S,2S)-3-(4-chlorophenyl)-2-(3-cyanophenyl)-1-methylpropyl]-2-methyl-2-[[5-(trifluoromethyl)pyridin-2-yl]oxy]propanamide (MK-0364), in rodents.

Fong TM, Guan XM, Marsh DJ, Shen CP, Stribling DS, Rosko KM, Lao J, Yu H, Feng Y, Xiao JC, Van der Ploeg LH, Goulet MT, Hagmann WK, Lin LS, Lanza TJ Jr, Jewell JP, Liu P, Shah SK, Qi H, Tong X, Wang J, Xu SS, Francis B, Strack AM, MacIntyre DE, Shearman LP. Fong TM, et al. Among authors: francis b. J Pharmacol Exp Ther. 2007 Jun;321(3):1013-22. doi: 10.1124/jpet.106.118737. Epub 2007 Feb 27. J Pharmacol Exp Ther. 2007. PMID: 17327489

2

Effects of mutations at conserved TM II residues on ligand binding and activation of mouse 5-HT6 receptor.

Zhang J, Shen CP, Xiao JC, Lanza TJ, Lin LS, Francis BE, Fong TM, Chen RZ. Zhang J, et al. Eur J Pharmacol. 2006 Mar 18;534(1-3):77-82. doi: 10.1016/j.ejphar.2006.01.049. Eur J Pharmacol. 2006. PMID: 16612839

3

Tachykinin NK1 receptor antagonists act centrally to inhibit emesis induced by the chemotherapeutic agent cisplatin in ferrets.

Tattersall FD, Rycroft W, Francis B, Pearce D, Merchant K, MacLeod AM, Ladduwahetty T, Keown L, Swain C, Baker R, Cascieri M, Ber E, Metzger J, MacIntyre DE, Hill RG, Hargreaves RJ. Tattersall FD, et al. Among authors: francis b. Neuropharmacology. 1996;35(8):1121-9. doi: 10.1016/s0028-3908(96)00020-2. Neuropharmacology. 1996. PMID: 9121615

4

The plasma-occupancy relationship of the novel GABAA receptor benzodiazepine site ligand, alpha5IA, is similar in rats and primates.

Atack JR, Eng WS, Gibson RE, Ryan C, Francis B, Sohal B, Dawson GR, Hargreaves RJ, Burns HD. Atack JR, et al. Among authors: francis b. Br J Pharmacol. 2009 Jul;157(5):796-803. doi: 10.1111/j.1476-5381.2009.00216.x. Epub 2009 Apr 30. Br J Pharmacol. 2009. PMID: 19422390 Free PMC article.

5

Characterization of specific binding of [125I]L-762,459, a selective alpha1A-adrenoceptor radioligand to rat and human tissues.

O'Malley SS, Chen TB, Francis BE, Gibson RE, Burns HD, DiSalvo J, Bayne ML, Wetzel JM, Nagarathnam D, Marzabadi M, Gluchowski C, Chang RS. O'Malley SS, et al. Among authors: francis be. Eur J Pharmacol. 1998 May 8;348(2-3):287-95. doi: 10.1016/s0014-2999(98)00149-6. Eur J Pharmacol. 1998. PMID: 9652345

6

In vitro studies on L-771,688 (SNAP 6383), a new potent and selective alpha1A-adrenoceptor antagonist.

Chang RS, Chen TB, O'Malley SS, Pettibone DJ, DiSalvo J, Francis B, Bock MG, Freidinger R, Nagarathnam D, Miao SW, Shen Q, Lagu B, Murali Dhar TG, Tyagarajan S, Marzabadi MR, Wong WC, Gluchowski C, Forray C. Chang RS, et al. Among authors: francis b. Eur J Pharmacol. 2000 Dec 15;409(3):301-12. doi: 10.1016/s0014-2999(00)00854-2. Eur J Pharmacol. 2000. PMID: 11108825

7

Radioiodinated L-703,606: a potent, selective antagonist to the human NK1 receptor.

Francis BE, Swain C, Sabin V, Burns HD. Francis BE, et al. Appl Radiat Isot. 1994 Jan;45(1):97-103. doi: 10.1016/0969-8043(94)90154-6. Appl Radiat Isot. 1994. PMID: 8287060

8

Radioiodinated endothelin-1: a radiotracer for imaging endothelin receptor distribution and occupancy.

Gibson RE, Fioravanti C, Francis B, Burns HD. Gibson RE, et al. Among authors: francis b. Nucl Med Biol. 1999 Feb;26(2):193-9. doi: 10.1016/s0969-8051(98)00085-7. Nucl Med Biol. 1999. PMID: 10100219

9

Non-invasive radiotracer imaging as a tool for drug development.

Gibson RE, Burns HD, Hamill TG, Eng WS, Francis BE, Ryan C. Gibson RE, et al. Among authors: francis be. Curr Pharm Des. 2000 Jul;6(10):973-89. doi: 10.2174/1381612003399987. Curr Pharm Des. 2000. PMID: 10828297 Review.

10

Positron emission tomography neuroreceptor imaging as a tool in drug discovery, research and development.

Burns HD, Hamill TG, Eng WS, Francis B, Fioravanti C, Gibson RE. Burns HD, et al. Among authors: francis b. Curr Opin Chem Biol. 1999 Aug;3(4):388-94. doi: 10.1016/S1367-5931(99)80059-3. Curr Opin Chem Biol. 1999. PMID: 10419855 Review.

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