Fraser CS - Search Results

1

The CXCR4-LASP1-eIF4F Axis Promotes Translation of Oncogenic Proteins in Triple-Negative Breast Cancer Cells.

Howard CM, Bearss N, Subramaniyan B, Tilley A, Sridharan S, Villa N, Fraser CS, Raman D. Howard CM, et al. Among authors: fraser cs. Front Oncol. 2019 Apr 24;9:284. doi: 10.3389/fonc.2019.00284. eCollection 2019. Front Oncol. 2019. PMID: 31106142 Free PMC article.

2

Functional reconstitution of human eukaryotic translation initiation factor 3 (eIF3).

Sun C, Todorovic A, Querol-Audí J, Bai Y, Villa N, Snyder M, Ashchyan J, Lewis CS, Hartland A, Gradia S, Fraser CS, Doudna JA, Nogales E, Cate JH. Sun C, et al. Among authors: fraser cs. Proc Natl Acad Sci U S A. 2011 Dec 20;108(51):20473-8. doi: 10.1073/pnas.1116821108. Epub 2011 Dec 1. Proc Natl Acad Sci U S A. 2011. PMID: 22135459 Free PMC article.

3

Human eukaryotic initiation factor 4G (eIF4G) protein binds to eIF3c, -d, and -e to promote mRNA recruitment to the ribosome.

Villa N, Do A, Hershey JW, Fraser CS. Villa N, et al. Among authors: fraser cs. J Biol Chem. 2013 Nov 15;288(46):32932-40. doi: 10.1074/jbc.M113.517011. Epub 2013 Oct 3. J Biol Chem. 2013. PMID: 24092755 Free PMC article.

4

Phosphorylation stoichiometries of human eukaryotic initiation factors.

Andaya A, Villa N, Jia W, Fraser CS, Leary JA. Andaya A, et al. Among authors: fraser cs. Int J Mol Sci. 2014 Jun 27;15(7):11523-38. doi: 10.3390/ijms150711523. Int J Mol Sci. 2014. PMID: 24979134 Free PMC article.

5

eIF5B and eIF1A reorient initiator tRNA to allow ribosomal subunit joining.

Lapointe CP, Grosely R, Sokabe M, Alvarado C, Wang J, Montabana E, Villa N, Shin BS, Dever TE, Fraser CS, Fernández IS, Puglisi JD. Lapointe CP, et al. Among authors: fraser cs. Nature. 2022 Jul;607(7917):185-190. doi: 10.1038/s41586-022-04858-z. Epub 2022 Jun 22. Nature. 2022. PMID: 35732735 Free PMC article.

6

Human eukaryotic initiation factor 4E (eIF4E) and the nucleotide-bound state of eIF4A regulate eIF4F binding to RNA.

Izidoro MS, Sokabe M, Villa N, Merrick WC, Fraser CS. Izidoro MS, et al. Among authors: fraser cs. J Biol Chem. 2022 Oct;298(10):102368. doi: 10.1016/j.jbc.2022.102368. Epub 2022 Aug 11. J Biol Chem. 2022. PMID: 35963437 Free PMC article.

7

Human eukaryotic initiation factor 4G directly binds the 40S ribosomal subunit to promote efficient translation.

Villa N, Fraser CS. Villa N, et al. Among authors: fraser cs. J Biol Chem. 2024 Apr 1;300(5):107242. doi: 10.1016/j.jbc.2024.107242. Online ahead of print. J Biol Chem. 2024. PMID: 38569933 Free article.

8

Cellular cap-binding protein, eIF4E, promotes picornavirus genome restructuring and translation.

Avanzino BC, Fuchs G, Fraser CS. Avanzino BC, et al. Among authors: fraser cs. Proc Natl Acad Sci U S A. 2017 Sep 5;114(36):9611-9616. doi: 10.1073/pnas.1704390114. Epub 2017 Aug 21. Proc Natl Acad Sci U S A. 2017. PMID: 28827335 Free PMC article.

9

Quantitative studies of mRNA recruitment to the eukaryotic ribosome.

Fraser CS. Fraser CS. Biochimie. 2015 Jul;114:58-71. doi: 10.1016/j.biochi.2015.02.017. Epub 2015 Mar 2. Biochimie. 2015. PMID: 25742741 Free PMC article. Review.

10

A helicase-independent activity of eIF4A in promoting mRNA recruitment to the human ribosome.

Sokabe M, Fraser CS. Sokabe M, et al. Among authors: fraser cs. Proc Natl Acad Sci U S A. 2017 Jun 13;114(24):6304-6309. doi: 10.1073/pnas.1620426114. Epub 2017 May 30. Proc Natl Acad Sci U S A. 2017. PMID: 28559306 Free PMC article.

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