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Mutant p53 disrupts mammary tissue architecture via the mevalonate pathway.
Freed-Pastor WA, Mizuno H, Zhao X, Langerød A, Moon SH, Rodriguez-Barrueco R, Barsotti A, Chicas A, Li W, Polotskaia A, Bissell MJ, Osborne TF, Tian B, Lowe SW, Silva JM, Børresen-Dale AL, Levine AJ, Bargonetti J, Prives C. Freed-Pastor WA, et al. Cell. 2012 Jan 20;148(1-2):244-58. doi: 10.1016/j.cell.2011.12.017. Cell. 2012. PMID: 22265415 Free PMC article.
Mutant p53: one name, many proteins.
Freed-Pastor WA, Prives C. Freed-Pastor WA, et al. Genes Dev. 2012 Jun 15;26(12):1268-86. doi: 10.1101/gad.190678.112. Genes Dev. 2012. PMID: 22713868 Free PMC article. Review.
p53 Represses the Mevalonate Pathway to Mediate Tumor Suppression.
Moon SH, Huang CH, Houlihan SL, Regunath K, Freed-Pastor WA, Morris JP 4th, Tschaharganeh DF, Kastenhuber ER, Barsotti AM, Culp-Hill R, Xue W, Ho YJ, Baslan T, Li X, Mayle A, de Stanchina E, Zender L, Tong DR, D'Alessandro A, Lowe SW, Prives C. Moon SH, et al. Among authors: freed pastor wa. Cell. 2019 Jan 24;176(3):564-580.e19. doi: 10.1016/j.cell.2018.11.011. Epub 2018 Dec 20. Cell. 2019. PMID: 30580964 Free PMC article.
Mutant p53 cooperates with the SWI/SNF chromatin remodeling complex to regulate VEGFR2 in breast cancer cells.
Pfister NT, Fomin V, Regunath K, Zhou JY, Zhou W, Silwal-Pandit L, Freed-Pastor WA, Laptenko O, Neo SP, Bargonetti J, Hoque M, Tian B, Gunaratne J, Engebraaten O, Manley JL, Børresen-Dale AL, Neilsen PM, Prives C. Pfister NT, et al. Genes Dev. 2015 Jun 15;29(12):1298-315. doi: 10.1101/gad.263202.115. Epub 2015 Jun 16. Genes Dev. 2015. PMID: 26080815 Free PMC article.
Accurate and sensitive quantification of protein-DNA binding affinity.
Rastogi C, Rube HT, Kribelbauer JF, Crocker J, Loker RE, Martini GD, Laptenko O, Freed-Pastor WA, Prives C, Stern DL, Mann RS, Bussemaker HJ. Rastogi C, et al. Proc Natl Acad Sci U S A. 2018 Apr 17;115(16):E3692-E3701. doi: 10.1073/pnas.1714376115. Epub 2018 Apr 2. Proc Natl Acad Sci U S A. 2018. PMID: 29610332 Free PMC article.
20 results