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A retroviral vector for siRNA expression in mammalian cells.
Størvold GL, Gjernes E, Askautrud HA, Børresen-Dale AL, Perou CM, Frengen E. Størvold GL, et al. Among authors: frengen e. Mol Biotechnol. 2007 Mar;35(3):275-82. doi: 10.1007/BF02686013. Mol Biotechnol. 2007. PMID: 17652791
STIM1 R304W causes muscle degeneration and impaired platelet activation in mice.
Gamage TH, Gunnes G, Lee RH, Louch WE, Holmgren A, Bruton JD, Lengle E, Kolstad TRS, Revold T, Amundsen SS, Dalen KT, Holme PA, Tjønnfjord GE, Christensen G, Westerblad H, Klungland A, Bergmeier W, Misceo D, Frengen E. Gamage TH, et al. Among authors: frengen e. Cell Calcium. 2018 Dec;76:87-100. doi: 10.1016/j.ceca.2018.10.001. Epub 2018 Oct 5. Cell Calcium. 2018. PMID: 30390422 Free PMC article.
STIM1 R304W in mice causes subgingival hair growth and an increased fraction of trabecular bone.
Gamage TH, Lengle E, Gunnes G, Pullisaar H, Holmgren A, Reseland JE, Merckoll E, Corti S, Mizobuchi M, Morales RJ, Tsiokas L, Tjønnfjord GE, Lacruz RS, Lyngstadaas SP, Misceo D, Frengen E. Gamage TH, et al. Among authors: frengen e. Cell Calcium. 2020 Jan;85:102110. doi: 10.1016/j.ceca.2019.102110. Epub 2019 Nov 13. Cell Calcium. 2020. PMID: 31785581 Free article.
siRNA: a potential tool for future breast cancer therapy?
Størvold GL, Andersen TI, Perou CM, Frengen E. Størvold GL, et al. Among authors: frengen e. Crit Rev Oncog. 2006 Jul;12(1-2):127-50. doi: 10.1615/critrevoncog.v12.i1-2.70. Crit Rev Oncog. 2006. PMID: 17078209 Review.
A single amino acid deletion in the ER Ca2+ sensor STIM1 reverses the in vitro and in vivo effects of the Stormorken syndrome-causing R304W mutation.
Gamage TH, Grabmayr H, Horvath F, Fahrner M, Misceo D, Louch WE, Gunnes G, Pullisaar H, Reseland JE, Lyngstadaas SP, Holmgren A, Amundsen SS, Rathner P, Cerofolini L, Ravera E, Krobath H, Luchinat C, Renger T, Müller N, Romanin C, Frengen E. Gamage TH, et al. Among authors: frengen e. Sci Signal. 2023 Feb 7;16(771):eadd0509. doi: 10.1126/scisignal.add0509. Epub 2023 Feb 7. Sci Signal. 2023. PMID: 36749824
83 results