Frey L - Search Results

1

Discovery of MK-4409, a Novel Oxazole FAAH Inhibitor for the Treatment of Inflammatory and Neuropathic Pain.

Chobanian HR, Guo Y, Liu P, Chioda MD, Fung S, Lanza TJ, Chang L, Bakshi RK, Dellureficio JP, Hong Q, McLaughlin M, Belyk KM, Krska SW, Makarewicz AK, Martel EJ, Leone JF, Frey L, Karanam B, Madeira M, Alvaro R, Shuman J, Salituro G, Terebetski JL, Jochnowitz N, Mistry S, McGowan E, Hajdu R, Rosenbach M, Abbadie C, Alexander JP, Shiao LL, Sullivan KM, Nargund RP, Wyvratt MJ, Lin LS, DeVita RJ. Chobanian HR, et al. Among authors: frey l. ACS Med Chem Lett. 2014 Apr 10;5(6):717-21. doi: 10.1021/ml5001239. eCollection 2014 Jun 12. ACS Med Chem Lett. 2014. PMID: 24944750 Free PMC article.

2

Discovery of a new cyclooxygenase-2 lead compound through 3-D database searching and combinatorial chemistry.

Stewart KD, Loren S, Frey L, Otis E, Klinghofer V, Hulkower KI. Stewart KD, et al. Among authors: frey l. Bioorg Med Chem Lett. 1998 Mar 3;8(5):529-34. doi: 10.1016/s0960-894x(98)00068-7. Bioorg Med Chem Lett. 1998. PMID: 9871612

3

Practical asymmetric synthesis of a selective endothelin A receptor (ETA) antagonist.

Song ZJ, Zhao M, Frey L, Li J, Tan L, Chen CY, Tschaen DM, Tillyer R, Grabowski EJ, Volante R, Reider PJ, Kato Y, Okada S, Nemoto T, Sato H, Akao A, Mase T. Song ZJ, et al. Among authors: frey l. Org Lett. 2001 Oct 18;3(21):3357-60. doi: 10.1021/ol016601s. Org Lett. 2001. PMID: 11594833

4

An investigation into causes and effects of high cyanide levels in the palladium-catalyzed cyanation reaction.

Marcantonio KM, Frey LF, Liu Y, Chen Y, Strine J, Phenix B, Wallace DJ, Chen CY. Marcantonio KM, et al. Org Lett. 2004 Oct 14;6(21):3723-5. doi: 10.1021/ol048643x. Org Lett. 2004. PMID: 15469333

5

Practical asymmetric synthesis of a potent PDE4 inhibitor via stereoselective enolate alkylation of a chiral aryl-heteroaryl secondary tosylate.

O'Shea PD, Chen CY, Chen W, Dagneau P, Frey LF, Grabowski EJ, Marcantonio KM, Reamer RA, Tan L, Tillyer RD, Roy A, Wang X, Zhao D. O'Shea PD, et al. Among authors: frey lf. J Org Chem. 2005 Apr 15;70(8):3021-30. doi: 10.1021/jo048156v. J Org Chem. 2005. PMID: 15822960

6

Identification and structural elucidation of process impurities generated in the end-game synthesis of taranabant (MK-0364) via cyanuric chloride.

Chen YW, Liu Y, Novak T, Frey L, Campos K, Klapars A, Chen CY, Phenix B. Chen YW, et al. Among authors: frey l. J Pharm Biomed Anal. 2009 Apr 5;49(3):702-10. doi: 10.1016/j.jpba.2009.01.003. Epub 2009 Jan 9. J Pharm Biomed Anal. 2009. PMID: 19188037

7

Efficacy and tolerability of diclofenac dispersible in painful osteoarthrosis.

Bakshi R, Ezzet N, Frey L, Lasry D, Salliere D. Bakshi R, et al. Among authors: frey l. Clin Rheumatol. 1993 Mar;12(1):57-61. doi: 10.1007/BF02231560. Clin Rheumatol. 1993. PMID: 7682167 Clinical Trial.

8

Evaluation of non-conventional polar modifiers on immobilized chiral stationary phases for improved resolution of enantiomers by supercritical fluid chromatography.

DaSilva JO, Coes B, Frey L, Mergelsberg I, McClain R, Nogle L, Welch CJ. DaSilva JO, et al. Among authors: frey l. J Chromatogr A. 2014 Feb 7;1328:98-103. doi: 10.1016/j.chroma.2013.12.073. Epub 2013 Dec 31. J Chromatogr A. 2014. PMID: 24456706

9

An electrically conducting 3D coronene-based metal-organic framework.

Schönherr MI, Scheurle PI, Frey L, Martínez-Abadía M, Döblinger M, Mähringer A, Fehn D, Gerhards L, Santourian I, Schirmacher A, Quast T, Wittstock G, Bein T, Meyer K, Mateo-Alonso A, Medina DD. Schönherr MI, et al. Among authors: frey l. J Mater Chem A Mater. 2024 Apr 19;12(17):10044-10049. doi: 10.1039/d3ta07120k. eCollection 2024 Apr 30. J Mater Chem A Mater. 2024. PMID: 38694264 Free PMC article.

10

Combined Hepatocellular-Cholangiocarcinoma: Biology, Diagnosis, and Management.

Ye L, Schneider JS, Ben Khaled N, Schirmacher P, Seifert C, Frey L, He Y, Geier A, De Toni EN, Zhang C, Reiter FP. Ye L, et al. Among authors: frey l. Liver Cancer. 2023 Apr 24;13(1):6-28. doi: 10.1159/000530700. eCollection 2024 Feb. Liver Cancer. 2023. PMID: 38344449 Free PMC article. Review.

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