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Page 1
Clinical features, treatment, and outcome of macrophage activation syndrome complicating systemic juvenile idiopathic arthritis: a multinational, multicenter study of 362 patients.
Minoia F, Davì S, Horne A, Demirkaya E, Bovis F, Li C, Lehmberg K, Weitzman S, Insalaco A, Wouters C, Shenoi S, Espada G, Ozen S, Anton J, Khubchandani R, Russo R, Pal P, Kasapcopur O, Miettunen P, Maritsi D, Merino R, Shakoory B, Alessio M, Chasnyk V, Sanner H, Gao YJ, Huasong Z, Kitoh T, Avcin T, Fischbach M, Frosch M, Grom A, Huber A, Jelusic M, Sawhney S, Uziel Y, Ruperto N, Martini A, Cron RQ, Ravelli A; Pediatric Rheumatology International Trials Organization; Childhood Arthritis and Rheumatology Research Alliance; Pediatric Rheumatology Collaborative Study Group; Histiocyte Society. Minoia F, et al. Among authors: frosch m. Arthritis Rheumatol. 2014 Nov;66(11):3160-9. doi: 10.1002/art.38802. Arthritis Rheumatol. 2014. PMID: 25077692
Development and initial validation of the MS score for diagnosis of macrophage activation syndrome in systemic juvenile idiopathic arthritis.
Minoia F, Bovis F, Davì S, Horne A, Fischbach M, Frosch M, Huber A, Jelusic M, Sawhney S, McCurdy DK, Silva CA, Rigante D, Unsal E, Ruperto N, Martini A, Cron RQ, Ravelli A; Pediatric Rheumatology International Trials Organization, the Childhood Arthritis & Rheumatology Research Alliance, the Pediatric Rheumatology Collaborative Study Group and the Histiocyte Society. Minoia F, et al. Among authors: frosch m. Ann Rheum Dis. 2019 Oct;78(10):1357-1362. doi: 10.1136/annrheumdis-2019-215211. Epub 2019 Jul 11. Ann Rheum Dis. 2019. PMID: 31296501
Two randomized trials of canakinumab in systemic juvenile idiopathic arthritis.
Ruperto N, Brunner HI, Quartier P, Constantin T, Wulffraat N, Horneff G, Brik R, McCann L, Kasapcopur O, Rutkowska-Sak L, Schneider R, Berkun Y, Calvo I, Erguven M, Goffin L, Hofer M, Kallinich T, Oliveira SK, Uziel Y, Viola S, Nistala K, Wouters C, Cimaz R, Ferrandiz MA, Flato B, Gamir ML, Kone-Paut I, Grom A, Magnusson B, Ozen S, Sztajnbok F, Lheritier K, Abrams K, Kim D, Martini A, Lovell DJ; PRINTO; PRCSG. Ruperto N, et al. N Engl J Med. 2012 Dec 20;367(25):2396-406. doi: 10.1056/NEJMoa1205099. N Engl J Med. 2012. PMID: 23252526 Free article. Clinical Trial.
Validation of relapse risk biomarkers for routine use in patients with juvenile idiopathic arthritis.
Rothmund F, Gerss J, Ruperto N, Däbritz J, Wittkowski H, Frosch M, Wulffraat NM, Wedderburn LR, Holzinger D, Gohar F, Vastert SJ, Brik R, Deslandre CJ, Melo-Gomes JA, Saad Magalhaes C, Barcellona R, Russo R, Gattorno M, Martini A, Roth J, Foell D; Paediatric Rheumatology International Trials Organisation (PRINTO). Rothmund F, et al. Among authors: frosch m. Arthritis Care Res (Hoboken). 2014 Jun;66(6):949-55. doi: 10.1002/acr.22248. Arthritis Care Res (Hoboken). 2014. PMID: 24339418 Free article. Clinical Trial.
Methotrexate withdrawal at 6 vs 12 months in juvenile idiopathic arthritis in remission: a randomized clinical trial.
Foell D, Wulffraat N, Wedderburn LR, Wittkowski H, Frosch M, Gerss J, Stanevicha V, Mihaylova D, Ferriani V, Tsakalidou FK, Foeldvari I, Cuttica R, Gonzalez B, Ravelli A, Khubchandani R, Oliveira S, Armbrust W, Garay S, Vojinovic J, Norambuena X, Gamir ML, García-Consuegra J, Lepore L, Susic G, Corona F, Dolezalova P, Pistorio A, Martini A, Ruperto N, Roth J; Paediatric Rheumatology International Trials Organization (PRINTO). Foell D, et al. Among authors: frosch m. JAMA. 2010 Apr 7;303(13):1266-73. doi: 10.1001/jama.2010.375. JAMA. 2010. PMID: 20371785 Clinical Trial.
Phagocyte-specific S100 proteins and high-sensitivity C reactive protein as biomarkers for a risk-adapted treatment to maintain remission in juvenile idiopathic arthritis: a comparative study.
Gerss J, Roth J, Holzinger D, Ruperto N, Wittkowski H, Frosch M, Wulffraat N, Wedderburn L, Stanevicha V, Mihaylova D, Harjacek M, Len C, Toppino C, Masi M, Minden K, Saurenmann T, Uziel Y, Vesely R, Apaz MT, Kuester RM, Elorduy MJ, Burgos-Vargas R, Ioseliani M, Magni-Manzoni S, Unsal E, Anton J, Balogh Z, Hagelberg S, Mazur-Zielinska H, Tauber T, Martini A, Foell D; Paediatric Rheumatology International Trials Organization (PRINTO). Gerss J, et al. Among authors: frosch m. Ann Rheum Dis. 2012 Dec;71(12):1991-7. doi: 10.1136/annrheumdis-2012-201329. Epub 2012 Jun 11. Ann Rheum Dis. 2012. PMID: 22689317 Clinical Trial.
S100A12 Is Associated with Response to Therapy in Juvenile Idiopathic Arthritis.
Gohar F, Anink J, Moncrieffe H, Van Suijlekom-Smit LWA, Prince FHM, van Rossum MAJ, Dolman KM, Hoppenreijs EPAH, Ten Cate R, Ursu S, Wedderburn LR, Horneff G, Frosch M, Foell D, Holzinger D. Gohar F, et al. Among authors: frosch m. J Rheumatol. 2018 Apr;45(4):547-554. doi: 10.3899/jrheum.170438. Epub 2018 Jan 15. J Rheumatol. 2018. PMID: 29335345 Free PMC article.
MRP8/14 serum levels as diagnostic markers for systemic juvenile idiopathic arthritis in children with prolonged fever.
Park C, Miranda-Garcia M, Berendes R, Horneff G, Kuemmerle-Deschner J, Ganser G, Huppertz HI, Minden K, Haas JP, Jansson AF, Borte M, Schuetz C, Oommen P, Frosch M, Schlueter B, Richter-Unruh A, Kessel C, Hinze C, Wittkowski H, Roth J, Foell D, Holzinger D. Park C, et al. Among authors: frosch m. Rheumatology (Oxford). 2022 Jul 6;61(7):3082-3092. doi: 10.1093/rheumatology/keab729. Rheumatology (Oxford). 2022. PMID: 34559193
Evidence-based, interdisciplinary guidelines for anti-inflammatory treatment of uveitis associated with juvenile idiopathic arthritis.
Heiligenhaus A, Michels H, Schumacher C, Kopp I, Neudorf U, Niehues T, Baus H, Becker M, Bertram B, Dannecker G, Deuter C, Foeldvari I, Frosch M, Ganser G, Gaubitz M, Gerdes G, Horneff G, Illhardt A, Mackensen F, Minden K, Pleyer U, Schneider M, Wagner N, Zierhut M; German Ophthalmological Society; Society for Childhood and Adolescent Rheumatology; German Society for Rheumatology. Heiligenhaus A, et al. Among authors: frosch m. Rheumatol Int. 2012 May;32(5):1121-33. doi: 10.1007/s00296-011-2126-1. Epub 2011 Nov 15. Rheumatol Int. 2012. PMID: 22083610 Review.
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