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The viral oncoprotein tax sequesters DNA damage response factors by tethering MDC1 to chromatin.
J Biol Chem. 2010 Oct 22;285(43):32897-32905. doi: 10.1074/jbc.M110.146373. Epub 2010 Aug 20.
J Biol Chem. 2010.
PMID: 20729195
Free PMC article.
Site-specific phosphorylation differentiates active from inactive forms of the human T-cell leukemia virus type 1 Tax oncoprotein.
Durkin SS, Ward MD, Fryrear KA, Semmes OJ.
Durkin SS, et al. Among authors: fryrear ka.
J Biol Chem. 2006 Oct 20;281(42):31705-12. doi: 10.1074/jbc.M607011200. Epub 2006 Aug 21.
J Biol Chem. 2006.
PMID: 16923801
Free article.
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HTLV-1 Tax oncoprotein subverts the cellular DNA damage response via binding to DNA-dependent protein kinase.
Durkin SS, Guo X, Fryrear KA, Mihaylova VT, Gupta SK, Belgnaoui SM, Haoudi A, Kupfer GM, Semmes OJ.
Durkin SS, et al. Among authors: fryrear ka.
J Biol Chem. 2008 Dec 26;283(52):36311-20. doi: 10.1074/jbc.M804931200. Epub 2008 Oct 27.
J Biol Chem. 2008.
PMID: 18957425
Free PMC article.
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Dimerization and a novel Tax speckled structure localization signal are required for Tax nuclear localization.
Fryrear KA, Durkin SS, Gupta SK, Tiedebohl JB, Semmes OJ.
Fryrear KA, et al.
J Virol. 2009 Jun;83(11):5339-52. doi: 10.1128/JVI.00232-09. Epub 2009 Mar 25.
J Virol. 2009.
PMID: 19321601
Free PMC article.
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The Sumo-targeted ubiquitin ligase RNF4 regulates the localization and function of the HTLV-1 oncoprotein Tax.
Fryrear KA, Guo X, Kerscher O, Semmes OJ.
Fryrear KA, et al.
Blood. 2012 Feb 2;119(5):1173-81. doi: 10.1182/blood-2011-06-358564. Epub 2011 Nov 21.
Blood. 2012.
PMID: 22106342
Free PMC article.
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