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Chromatin remodeler sucrose nonfermenting 2 homolog (SNF2H) is recruited onto DNA replication origins through interaction with Cdc10 protein-dependent transcript 1 (Cdt1) and promotes pre-replication complex formation.
Sugimoto N, Yugawa T, Iizuka M, Kiyono T, Fujita M. Sugimoto N, et al. Among authors: fujita m. J Biol Chem. 2011 Nov 11;286(45):39200-10. doi: 10.1074/jbc.M111.256123. Epub 2011 Sep 20. J Biol Chem. 2011. PMID: 21937426 Free PMC article.
Cdt1-binding protein GRWD1 is a novel histone-binding protein that facilitates MCM loading through its influence on chromatin architecture.
Sugimoto N, Maehara K, Yoshida K, Yasukouchi S, Osano S, Watanabe S, Aizawa M, Yugawa T, Kiyono T, Kurumizaka H, Ohkawa Y, Fujita M. Sugimoto N, et al. Among authors: fujita m. Nucleic Acids Res. 2015 Jul 13;43(12):5898-911. doi: 10.1093/nar/gkv509. Epub 2015 May 18. Nucleic Acids Res. 2015. PMID: 25990725 Free PMC article.
TRF2 recruits ORC through TRFH domain dimerization.
Higa M, Kushiyama T, Kurashige S, Kohmon D, Enokitani K, Iwahori S, Sugimoto N, Yoshida K, Fujita M. Higa M, et al. Among authors: fujita m. Biochim Biophys Acta Mol Cell Res. 2017 Jan;1864(1):191-201. doi: 10.1016/j.bbamcr.2016.11.004. Epub 2016 Nov 9. Biochim Biophys Acta Mol Cell Res. 2017. PMID: 27836746 Free article.
Two E3 ubiquitin ligases, SCF-Skp2 and DDB1-Cul4, target human Cdt1 for proteolysis.
Nishitani H, Sugimoto N, Roukos V, Nakanishi Y, Saijo M, Obuse C, Tsurimoto T, Nakayama KI, Nakayama K, Fujita M, Lygerou Z, Nishimoto T. Nishitani H, et al. Among authors: fujita m. EMBO J. 2006 Mar 8;25(5):1126-36. doi: 10.1038/sj.emboj.7601002. Epub 2006 Feb 16. EMBO J. 2006. PMID: 16482215 Free PMC article.
5,244 results