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Neisseria meningitidis and Escherichia coli are protected from leukocyte phagocytosis by binding to erythrocyte complement receptor 1 in human blood.
Brekke OL, Hellerud BC, Christiansen D, Fure H, Castellheim A, Nielsen EW, Pharo A, Lindstad JK, Bergseth G, Leslie G, Lambris JD, Brandtzaeg P, Mollnes TE. Brekke OL, et al. Among authors: fure h. Mol Immunol. 2011 Sep;48(15-16):2159-69. doi: 10.1016/j.molimm.2011.07.011. Epub 2011 Aug 11. Mol Immunol. 2011. PMID: 21839519 Free PMC article.
Combined inhibition of C5 and CD14 efficiently attenuated the inflammatory response in a porcine model of meningococcal sepsis.
Hellerud BC, Orrem HL, Dybwik K, Pischke SE, Baratt-Due A, Castellheim A, Fure H, Bergseth G, Christiansen D, Nunn MA, Espevik T, Lau C, Brandtzæg P, Nielsen EW, Mollnes TE. Hellerud BC, et al. Among authors: fure h. J Intensive Care. 2017 Feb 27;5:21. doi: 10.1186/s40560-017-0217-0. eCollection 2017. J Intensive Care. 2017. PMID: 28261486 Free PMC article.
Key role of the number of complement receptor 1 on erythrocytes for binding of Escherichia coli to erythrocytes and for leukocyte phagocytosis and oxidative burst in human whole blood.
Brekke OL, Christiansen D, Kisserli A, Fure H, Dahl JA, Donvito B, Reveil B, Ludviksen JK, Tabary T, Mollnes TE, Cohen JHM. Brekke OL, et al. Among authors: fure h. Mol Immunol. 2019 Oct;114:139-148. doi: 10.1016/j.molimm.2019.07.014. Epub 2019 Jul 25. Mol Immunol. 2019. PMID: 31352230
A Conformational Change of Complement C5 Is Required for Thrombin-Mediated Cleavage, Revealed by a Novel Ex Vivo Human Whole Blood Model Preserving Full Thrombin Activity.
Nilsson PH, Johnson C, Quach QH, Macpherson A, Durrant O, Pischke SE, Fure H, Landsem A, Bergseth G, Schjalm C, Haugaard-Kedström LM, Huber-Lang M, van den Elsen J, Brekke OL, Mollnes TE. Nilsson PH, et al. Among authors: fure h. J Immunol. 2021 Sep 15;207(6):1641-1651. doi: 10.4049/jimmunol.2001471. Epub 2021 Aug 11. J Immunol. 2021. PMID: 34380648 Free PMC article.
37 results