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Mitotic cells form actin-based bridges with adjacent cells to provide intercellular communication during rounding.
Cell Cycle. 2016 Nov;15(21):2943-2957. doi: 10.1080/15384101.2016.1231280. Epub 2016 Sep 13.
Cell Cycle. 2016.
PMID: 27625181
Free PMC article.
Smad ubiquitination regulatory factor-2 controls gap junction intercellular communication by modulating endocytosis and degradation of connexin43.
Fykerud TA, Kjenseth A, Schink KO, Sirnes S, Bruun J, Omori Y, Brech A, Rivedal E, Leithe E.
Fykerud TA, et al.
J Cell Sci. 2012 Sep 1;125(Pt 17):3966-76. doi: 10.1242/jcs.093500. Epub 2012 May 23.
J Cell Sci. 2012.
PMID: 22623726
Item in Clipboard
The E3 ubiquitin ligase NEDD4 induces endocytosis and lysosomal sorting of connexin 43 to promote loss of gap junctions.
Totland MZ, Bergsland CH, Fykerud TA, Knudsen LM, Rasmussen NL, Eide PW, Yohannes Z, Sørensen V, Brech A, Lothe RA, Leithe E.
Totland MZ, et al. Among authors: fykerud ta.
J Cell Sci. 2017 Sep 1;130(17):2867-2882. doi: 10.1242/jcs.202408. Epub 2017 Jul 21.
J Cell Sci. 2017.
PMID: 28733455
Item in Clipboard
Regulation of gap junction intercellular communication by the ubiquitin system.
Kjenseth A, Fykerud T, Rivedal E, Leithe E.
Kjenseth A, et al.
Cell Signal. 2010 Sep;22(9):1267-73. doi: 10.1016/j.cellsig.2010.03.005. Epub 2010 Mar 4.
Cell Signal. 2010.
PMID: 20206687
Review.
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Endocytosis and post-endocytic sorting of connexins.
Leithe E, Sirnes S, Fykerud T, Kjenseth A, Rivedal E.
Leithe E, et al.
Biochim Biophys Acta. 2012 Aug;1818(8):1870-9. doi: 10.1016/j.bbamem.2011.09.029. Epub 2011 Oct 4.
Biochim Biophys Acta. 2012.
PMID: 21996040
Free article.
Review.
Item in Clipboard
The gap junction channel protein connexin 43 is covalently modified and regulated by SUMOylation.
Kjenseth A, Fykerud TA, Sirnes S, Bruun J, Yohannes Z, Kolberg M, Omori Y, Rivedal E, Leithe E.
Kjenseth A, et al. Among authors: fykerud ta.
J Biol Chem. 2012 May 4;287(19):15851-61. doi: 10.1074/jbc.M111.281832. Epub 2012 Mar 12.
J Biol Chem. 2012.
PMID: 22411987
Free PMC article.
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Connexins in colorectal cancer pathogenesis.
Sirnes S, Lind GE, Bruun J, Fykerud TA, Mesnil M, Lothe RA, Rivedal E, Kolberg M, Leithe E.
Sirnes S, et al. Among authors: fykerud ta.
Int J Cancer. 2015 Jul 1;137(1):1-11. doi: 10.1002/ijc.28911. Epub 2014 May 5.
Int J Cancer. 2015.
PMID: 24752574
Free article.
Review.
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NEDD4 is overexpressed in colorectal cancer and promotes colonic cell growth independently of the PI3K/PTEN/AKT pathway.
Eide PW, Cekaite L, Danielsen SA, Eilertsen IA, Kjenseth A, Fykerud TA, Ågesen TH, Bruun J, Rivedal E, Lothe RA, Leithe E.
Eide PW, et al. Among authors: fykerud ta.
Cell Signal. 2013 Jan;25(1):12-8. doi: 10.1016/j.cellsig.2012.08.012. Epub 2012 Sep 5.
Cell Signal. 2013.
PMID: 22974840
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